Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis

C Dieter, LA Brondani, CB Leitão, F Gerchman… - PLoS …, 2022 - journals.plos.org
Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

Individual genetic variability mainly of Proinflammatory cytokines, cytokine receptors, and toll‐like receptors dictates pathophysiology of COVID‐19 disease

MK Vakil, Y Mansoori, GRL Al‐Awsi… - Journal of Medical …, 2022 - Wiley Online Library
Innate and acquired immunity responses are crucial for viral infection elimination. However,
genetic variations in coding genes may exacerbate the inflammation or initiate devastating …

Association between interleukin-10 gene polymorphisms (rs1800871, rs1800872, and rs1800896) and severity of infection in different SARS-CoV-2 variants

SJA Abbood, E Anvari, A Fateh - Human Genomics, 2023 - Springer
Background Polymorphisms in the interleukin-10 (IL10) gene have been linked to the
severity of the patients infected with the viral infections. This study aimed to assess if the …

A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines

G Abdolmaleki, MA Taheri, S Paridehpour… - DARU Journal of …, 2022 - Springer
Since the outbreak of the novel coronavirus disease 2019 (COVID-19) in Wuhan, China,
many health care systems have been heavily engaged in treating and preventing the …

Genetics of COVID‐19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review

M Tziastoudi, C Cholevas, I Stefanidis… - Annals of Clinical …, 2022 - Wiley Online Library
Abstract COVID‐19 and ME/CFS present with some similar symptoms, especially physical
and mental fatigue. In order to understand the basis of these similarities and the possibility of …

Implication of single nucleotide polymorphisms in Interleukin-10 gene (rs1800896 and rs1800872) with severity of COVID-19

S Rizvi, SMS Rizvi, ST Raza, M Abbas, K Fatima… - Egyptian Journal of …, 2022 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) is an ongoing pandemic which
has emerged as a new challenge for the medical sciences. Severity of COVID-19 is mostly …

Association of IL-10 gene in protection against COVID-19 disease

N Sheikhi, M Jamalidoust, K Shahzamani… - Jundishapur Journal …, 2023 - eprints.lums.ac.ir
Background: The medical community is facing a new challenge with the coronavirus disease
2019 (COVID-19) pandemic, as the severity of the disease is largely determined by the …

Biomarkers of immunothrombosis and polymorphisms of IL2, IL6, and IL10 genes as predictors of the severity of COVID-19 in a Kazakh population

A Yessenbayeva, B Apsalikov, M Massabayeva… - Plos one, 2023 - journals.plos.org
Objectives To study the role of biological markers of immunothrombosis and polymorphisms
of cytokine genes IL2, IL6, IL10 and their influence on the severity of COVID-19 in a Kazakh …

Association of IL6 and IL10 gene promotor polymorphisms with susceptibility to acute necrotizing encephalopathy

A Hoshino, N Takahashi, A Oka… - Frontiers in …, 2023 - frontiersin.org
Objective Acute necrotizing encephalopathy (ANE) is a severe complication of infectious
diseases affecting the brain and systemic organs. The main pathogenesis is cytokine storm …