MicroRNAs in stress signaling and human disease

JT Mendell, EN Olson - Cell, 2012 - cell.com
Disease is often the result of an aberrant or inadequate response to physiologic and
pathophysiologic stress. Studies over the last 10 years have uncovered a recurring …

MicroRNA-206: the skeletal muscle-specific myomiR

JJ McCarthy - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2008 - Elsevier
MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene
silencing. A small number of striated muscle-specific miRNAs have been identified and …

PolymiRTS Database 3.0: linking polymorphisms in microRNAs and their target sites with human diseases and biological pathways

A Bhattacharya, JD Ziebarth, Y Cui - Nucleic acids research, 2014 - academic.oup.com
Poly morphisms in mi cro R NAs (miRNAs) and their t arget s ites (PolymiRTS) are known to
disrupt miRNA function, leading to the development of disease and variation in physiological …

Genome‐wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis

J Gong, Y Tong, HM Zhang, K Wang, T Hu… - Human …, 2012 - Wiley Online Library
MicroRNAs (miRNAs) are studied as key regulators of gene expression involved in different
diseases. Several single nucleotide polymorphisms (SNPs) in miRNA genes or target sites …

MicroRNA target site polymorphisms and human disease

P Sethupathy, FS Collins - Trends in genetics, 2008 - cell.com
MicroRNAs (miRNAs) are important regulators of eukaryotic gene expression. They have
been implicated in a broad range of biological processes, and miRNA-related genetic …

MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine

PJ Mishra, JR Bertino - Pharmacogenomics, 2009 - Taylor & Francis
Referred to as the micromanagers of gene expression, microRNAs (miRNAs) are
evolutionarily conserved small noncoding RNAs. Polymorphisms in the miRNA pathway …

Polymorphisms in microRNA targets: a gold mine for molecular epidemiology

K Chen, F Song, GA Calin, Q Wei, X Hao… - …, 2008 - academic.oup.com
MicroRNAs are non-coding small RNAs that regulate gene expression by Watson–Crick
base pairing to target messenger RNA (mRNA). They are involved in most biological and …

miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes

AE Bruno, L Li, JL Kalabus, Y Pan, A Yu, Z Hu - BMC genomics, 2012 - Springer
Abstract Background Single nucleotide polymorphisms (SNPs) can lead to the susceptibility
and onset of diseases through their effects on gene expression at the posttranscriptional …

Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant

YQ Song, T Karasugi, KMC Cheung… - The Journal of …, 2013 - Am Soc Clin Investig
Lumbar disc degeneration (LDD) is associated with both genetic and environmental factors
and affects many people worldwide. A hallmark of LDD is loss of proteoglycan and water …

SomamiR 2.0: a database of cancer somatic mutations altering microRNA–ceRNA interactions

A Bhattacharya, Y Cui - Nucleic acids research, 2016 - academic.oup.com
Abstract SomamiR 2.0 (http://compbio. uthsc. edu/SomamiR) is a database of cancer
somatic mutations in microRNAs (miRNA) and their target sites that potentially alter the …