Parkinson's disease (PD) is characterized by dopaminergic (DA) neuron loss and the
formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is …

There are over 15 disease-modifying drugs that have been approved over the last 20 years
for the treatment of relapsing–remitting multiple sclerosis (MS), but there are limited …

Metallomodulation cell death strategies are extensively investigated for antitumor therapy,
such as cuproptosis, ferroptosis, and chemodynamic therapy (CDT). Undoubtedly, the …

Background Inflammatory response mediated by oxidative stress is considered as an
important pathogenesis of spinal cord injury (SCI). Advanced oxidation protein products …

Intracerebral hemorrhage (ICH) is a highly fatal disease with mortality rate of approximately
50%. Oxidative stress (OS) is a prominent cause of brain injury in ICH. Important sources of …

Parkinson's disease (PD) is a slowly progressive neurodegenerative disease characterized
by α-synuclein aggregation and dopaminergic neuronal death. Recent evidence suggests …

Chemodynamic therapy (CDT) involves the catalytic generation of highly toxic hydroxyl
radicals (. OH) from hydrogen peroxide (H2O2) through metal‐ion‐mediated Fenton or …

The blood‐brain barrier (BBB), as a crucial gate of brain‐blood molecular exchange, is
involved in the pathogenesis of multiple neurological diseases. Oxidative stress is caused …

Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …

Iron is an essential element for multiple fundamental biological processes required for life;
yet iron overload can be cytotoxic. Consequently, iron concentrations at the cellular and …