The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

The etiology of preeclampsia is unknown. At present, 4 hypotheses are the subject of
extensive investigation, as follows:(1) Placental ischemia—Increased trophoblast …

Miscarriage and pre-eclampsia are the most common disorders of human pregnancy. Both
are placental-related and exceptional in other mammalian species. Ultrasound imaging has …

Embryo implantation in higher primates is mediated by trophoblast: in the earliest phases by
syncytiotrophoblast, then by both cytotrophoblast and syncytiotrophoblast. In the course of …

In this paper definitive evidence that the classical class I product, HLA-C, is expressed on
the surface of normal trophoblast cells is provided. HLA-C transcripts were sequenced from …

This book explains and reviews some of the significant events involved in human
implantation and the establishment of the placenta in the uterus. This critical phase in …

The human placenta represents an abundant; easily accessible and unlimited study material
(at birth a human placenta provides about 500g of trophoblast). Cytotrophoblastic cells …

Although replete with cytotoxic machinery, uterine NK (uNK) cells remain tolerant at the
maternal-fetal interface. The mechanisms that facilitate the uNK cell tolerance are largely …

The maternal syndrome of pre-eclampsia is thought to result from endothelial cell damage
caused by a circulating factor derived from the placenta. This study investigates the …

Although the role of melatonin on fetal development has been the subject of a number of
studies, little is known about the function of melatonin in the placenta. We previously showed …