The role of glutamate signaling in the pathogenesis and treatment of obsessive–compulsive disorder

K Wu, GL Hanna, DR Rosenberg, PD Arnold - … Biochemistry and Behavior, 2012 - Elsevier
Obsessive–compulsive disorder (OCD) is a common and often debilitating neuropsychiatric
condition characterized by persistent intrusive thoughts (obsessions), repetitive ritualistic …

The obsessive compulsive spectrum in schizophrenia, a meta-analysis and meta-regression exploring prevalence rates

M Swets, J Dekker… - Schizophrenia …, 2014 - Elsevier
Aims The aims of this study were to conduct a meta-analysis and meta-regression to
estimate the prevalence rates for obsessive compulsive symptoms (OCS) and obsessive …

[HTML][HTML] Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors

F Schirmbeck, M Zink - Frontiers in pharmacology, 2013 - frontiersin.org
A large subgroup of around 25% of schizophrenia patients suffers from obsessive-
compulsive symptoms (OCS) and about 12% fulfill the diagnostic criteria of an obsessive …

Clozapine-induced obsessive-compulsive symptoms in schizophrenia: a critical review

F Schirmbeck, M Zink - Current Neuropharmacology, 2012 - ingentaconnect.com
Obsessive-compulsive disorder (OCD) is rarely associated with schizophrenia, whereas 20
to 30% of schizophrenic patients, suffer from comorbid obsessive-compulsive symptoms …

Antiserotonergic antipsychotics are associated with obsessive–compulsive symptoms in schizophrenia

F Schirmbeck, C Esslinger, F Rausch… - Psychological …, 2011 - cambridge.org
BackgroundEpidemiological investigations show that up to 30% of schizophrenic patients
suffer from obsessive–compulsive symptoms (OCS) associated with negative impact on the …

Second generation antipsychotic-induced obsessive-compulsive symptoms in schizophrenia: a review of the experimental literature

TM Fonseka, MA Richter, DJ Müller - Current psychiatry reports, 2014 - Springer
Second generation antipsychotics (SGAs) have been implicated in the de novo emergence
and exacerbation of obsessive-compulsive symptoms (OCS) in patients with schizophrenia …

Antipsychotics and obsessive–compulsive disorder/obsessive–compulsive symptoms: A pharmacovigilance study of the FDA adverse event reporting system

BG Burk, T DiGiacomo, S Polancich… - Acta Psychiatrica …, 2023 - Wiley Online Library
Objective Antipsychotics have conflicting data with respect to obsessive–compulsive
disorder/symptoms (OCD/OCS), with some reporting causality and some reporting treatment …

Association of the glutamate transporter gene SLC1A1 with atypical antipsychotics–induced obsessive-compulsive symptoms

JS Kwon, YH Joo, HJ Nam, M Lim… - Archives of general …, 2009 - jamanetwork.com
Context Several studies have indicated that atypical antipsychotics (AAP) induce obsessive-
compulsive (OC) symptoms. Research exploring the mechanism of this phenomenon …

Clozapine-induced obsessive-compulsive syndromes improve in combination with aripiprazole

S Englisch, C Esslinger, D Inta… - Clinical …, 2009 - journals.lww.com
Patients with schizophrenia often experience comorbid obsessive-compulsive syndromes
(OCSs). Within these patients, a significant subgroup developed secondary OCS during …

[HTML][HTML] Comorbid obsessive-compulsive symptoms in schizophrenia: insight into pathomechanisms facilitates treatment

M Zink - Advances in medicine, 2014 - hindawi.com
Insight into the biological pathomechanism of a clinical syndrome facilitates the
development of effective interventions. This paper applies this perspective to the important …