[HTML][HTML] Psychoactive drugs—from chemical structure to oxidative stress related to dopaminergic neurotransmission. A review

G Jîtcă, BE Ősz, A Tero-Vescan, CE Vari - Antioxidants, 2021 - mdpi.com
Nowadays, more and more young people want to experience illegal, psychoactive
substances, without knowing the risks of exposure. Besides affecting social life …

Neurotoxicology of synthetic cathinone analogs

M Angoa-Pérez, JH Anneken, DM Kuhn - Neuropharmacology of New …, 2017 - Springer
The present review briefly explores the neurotoxic properties of methcathinone,
mephedrone, methylone, and methylenedioxypyrovalerone (MDPV), four synthetic …

A structure–activity study of aromatic acid modulators for the synthesis of zirconium-based metal–organic frameworks

FE Chen, TA Pitt, DJ Okong'o, LG Wetherbee… - Chemistry of …, 2022 - ACS Publications
Acid modulation is among the most widely employed methods for preparing metal–organic
frameworks (MOFs) that are both stable and highly crystalline, yet there exist few guiding …

Neuropharmacology of synthetic cathinones

MH Baumann, HM Walters, M Niello… - … , Clinical, Forensic and …, 2018 - Springer
Synthetic cathinones are derivatives of the naturally occurring compound cathinone, the
main psychoactive ingredient in the khat plant Catha edulis. Cathinone is the β-keto analog …

[HTML][HTML] Serotonin-releasing agents with reduced off-target effects

FP Mayer, M Niello, D Cintulova, S Sideromenos… - Molecular …, 2023 - nature.com
Increasing extracellular levels of serotonin (5-HT) in the brain ameliorates symptoms of
depression and anxiety-related disorders, eg, social phobias and post-traumatic stress …

Structure-activity relationships of bath salt components: substituted cathinones and benzofurans at biogenic amine transporters

AJ Eshleman, S Nagarajan, KM Wolfrum, JF Reed… - …, 2019 - Springer
Abstract Rationale New psychoactive substances (NPSs), including substituted cathinones
and other stimulants, are synthesized, sold on the Internet, and ingested without knowledge …

Structure-activity relationships of synthetic cathinones

RA Glennon, M Dukat - … of New Psychoactive Substances (NPS) The …, 2017 - Springer
Until recently, there was rather little interest in the structure-activity relationships (SARs) of
cathinone analogs because so few agents were available and because they represented a …

[HTML][HTML] α-PPP and its derivatives are selective partial releasers at the human norepinephrine transporter: a pharmacological characterization of interactions between …

J Maier, L Rauter, D Rudin, M Niello, M Holy… - …, 2021 - Elsevier
While classical cathinones, such as methcathinone, have been shown to be monoamine
releasing agents at human monoamine transporters, the subgroup of α-pyrrolidinophenones …

Quantitative structure–activity relationship analysis of the pharmacology of para‐substituted methcathinone analogues

JS Bonano, ML Banks, R Kolanos… - British journal of …, 2015 - Wiley Online Library
Background and Purpose Methcathinone (MCAT) is a potent monoamine releaser and
parent compound to emerging drugs of abuse including mephedrone (4‐CH 3 MCAT), the …

Abuse-related neurochemical effects of para-substituted methcathinone analogs in rats: microdialysis studies of nucleus accumbens dopamine and serotonin

JA Suyama, F Sakloth, R Kolanos, RA Glennon… - … of Pharmacology and …, 2016 - ASPET
Methcathinone (MCAT) is a monoamine releaser and parent compound to a new class of
designer drugs that includes the synthetic cathinones mephedrone and flephedrone. Using …