The role of gut microbiota in various neurological and psychiatric disorders—an evidence mapping based on quantified evidence

Y Zang, X Lai, C Li, D Ding, Y Wang… - Mediators of …, 2023 - Wiley Online Library
Background and Object. There is a growing body of evidence highlighting the significant role
of gut microbiota in various neurological and psychiatric disorders. We performed an …

Effect of nutrition in Alzheimer's disease: A systematic review

I Xu Lou, K Ali, Q Chen - Frontiers in Neuroscience, 2023 - frontiersin.org
Background and objective Alzheimer's disease (AD) is a progressive neurodegenerative
disease characterized by declining cognitive ability. Currently, there are no effective …

A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders

EO Adewuyi, EK O'Brien, DR Nyholt, T Porter… - Communications …, 2022 - nature.com
Consistent with the concept of the gut-brain phenomenon, observational studies suggest a
relationship between Alzheimer's disease (AD) and gastrointestinal tract (GIT) disorders; …

[HTML][HTML] Targeting NLRP3 inflammasome modulates gut microbiota, attenuates corticospinal tract injury and ameliorates neurobehavioral deficits after intracerebral …

L Xiao, H Zheng, J Li, M Zeng, D He, J Liang… - Biomedicine & …, 2022 - Elsevier
Intracerebral hemorrhage (ICH) has a high mortality and disability rate. Fewer studies focus
on white matter injury (WMI) after ICH, especially the corticospinal tract (CST) injury located …

Sesamol attenuates amyloid peptide accumulation and cognitive deficits in APP/PS1 mice: The mediating role of the gut–brain axis

Q Liu, T Xie, Y Xi, L Li, F Mo, X Liu, Z Liu… - Journal of Agricultural …, 2021 - ACS Publications
Alzheimer's disease (AD), a neurodegenerative disease, is the leading cause of dementia.
Sesamol is a lignan extracted from sesame oil and has been found to exert neuroprotective …

Helicobacter pylori-Related Extraintestinal Manifestations—Myth or Reality

CD Mărginean, CO Mărginean, LE Meliț - Children, 2022 - mdpi.com
It is well documented that Helicobacter pylori (H. pylori) can cause both gastrointestinal and
extraintestinal manifestations. The latter one represents a major burden in terms of …

Marine natural products from the Russian Pacific as sources of drugs for neurodegenerative diseases

YS Khotimchenko, DN Silachev, VL Katanaev - Marine Drugs, 2022 - mdpi.com
Neurodegenerative diseases are growing to become one of humanity's biggest health
problems, given the number of individuals affected by them. They cause enough mortalities …

Alterations in the gut microbiota and metabolite profiles in the context of neuropathic pain

P Chen, C Wang, Y Ren, Z Ye, C Jiang, Z Wu - Molecular Brain, 2021 - Springer
The aim of this study was to explore the relationships among gut microbiota disturbances
and serum and spinal cord metabolic disorders in neuropathic pain. 16S rDNA amplicon …

Peripheral inflammation is a potential etiological factor in Alzheimer's disease

Z Li, H Wang, Y Yin - Reviews in the Neurosciences, 2024 - degruyter.com
Peripheral inflammation could constitute a risk factor for AD. This review summarizes the
research related to peripheral inflammation that appears to have a relationship with …

[HTML][HTML] The gut microbiota attenuate neuroinflammation in manganese exposure by inhibiting cerebral NLRP3 inflammasome

H Wang, F Yang, R Xin, D Cui, J He, S Zhang… - Biomedicine & …, 2020 - Elsevier
Manganese (Mn) exposure has been reported to cause neurodegenerative disorders. β-
Amyloid (Aβ) induced Tau pathology in an NLRP3-dependent manner is at the heart of …