The development of new techniques to rapidly and accurately detect bacteria has drawn
continuous attention due to the potential threats posed by bacteria to human health and …

A fluorescent probe 1 based on julolidine-chalcone derivative, which can specifically
recognize aluminum ion with high selectivity and anti-interference, was developed. Probe 1 …

As bacterial keratitis progresses rapidly, prompt intervention is necessary. Current
diagnostic processes are time-consuming and invasive, leading to improper antibiotics for …

For the first time, a series of vinyl sulfone-NH2-based push–pull fluorophores (4a–4d) were
introduced for their potential use in biological applications. The fluorophores 4a–4d were …

Nitroreductases are the enzymes that can convert nitroaromatic substances including
explosives like TNT to their corresponding nitrite, hydroxylamine or amino derivatives with …

In this paper, the natural chalcones: 2′-hydroxy-4, 4′, 6′-trimethoxychalcone (HCH),
cardamonin (CA), xanthohumol (XN), isobavachalcone (IBC) and licochalcone A (LIC) are …

This work focuses on preparation and optical characterization of the phenylene-thienyl
chalcone derivatives with various terminal groups–amino (3a), hydroxyl (3b) and carboxyl …

A direct chalcone to pyrazole synthetic route to “turn on” and “turn off” fluorescent sensors for
Cd2+ and Zn2+ was developed using using CuCl2 as an in situ oxidant. This one-pot …

摘要氨肽酶N (APN) 是一种广泛存在于生物体内的水解酶, 主要负责水解蛋白质多肽链N
端的中性或碱性氨基酸. APN 的过量表达与肿瘤, 药物性肝损伤, 急性肾损伤等多种生物功能 …

Chalcone derivatives are frequently found in bioactive compounds, natural products, and
pharmaceuticals. In this study, we developed a KO t Bu/DMF catalytic system to efficiently …