[HTML][HTML] Erectile dysfunction: Treatments, advances and new therapeutic strategies

A Argiolas, FM Argiolas, G Argiolas, MR Melis - Brain Sciences, 2023 - mdpi.com
Erectile dysfunction (ED) is the inability to get and maintain an adequate penile erection for
satisfactory sexual intercourse. Due to its negative impacts on men's life quality and increase …

[HTML][HTML] The effect of phosphodiesterase-type 5 inhibitors on erectile function: an overview of systematic reviews

N Pyrgidis, I Mykoniatis, AB Haidich, M Tirta… - Frontiers in …, 2021 - frontiersin.org
Background: Multiple systematic reviews explore the effect of phosphodiesterase type 5
(PDE5) inhibitors on erectile dysfunction (ED), with each study addressing specific …

Effect of phosphodiesterase type 5 inhibitors on major adverse cardiovascular events and overall mortality in a large nationwide cohort of men with erectile dysfunction …

RA Kloner, E Stanek, CL Crowe… - The journal of sexual …, 2023 - academic.oup.com
Background Treatment with phosphodiesterase type 5 inhibitors (PDE-5is) is effective in
treating erectile dysfunction (ED). Aim The objective of this study was to determine the effect …

Pyroptosis and inflammation‑mediated endothelial dysfunction may act as key factors in the development of erectile dysfunction

B Zhu, Y Niu, H Guo, X Jin, F Liu - Molecular Medicine …, 2023 - spandidos-publications.com
Erectile dysfunction (ED) is a prevalent disease that causes sexual dysfunction in males.
Inflammation‑induced endothelial dysfunction is a fundamental pathophysiological symptom …

[HTML][HTML] Oxidative Stress and Erectile Dysfunction: Pathophysiology, Impacts, and Potential Treatments

A Kaltsas, A Zikopoulos, F Dimitriadis, D Sheshi… - Current Issues in …, 2024 - mdpi.com
Erectile dysfunction (ED) is a prevalent condition affecting men's sexual health, with
oxidative stress (OS) having recently been identified as a significant contributing causative …

The effect of combination treatment with low-intensity shockwave therapy and Tadalafil on mild and mild-to-moderate erectile dysfunction: a double-blind, randomized …

I Mykoniatis, N Pyrgidis, F Zilotis… - The journal of sexual …, 2022 - academic.oup.com
Background Combination of different first-line treatments for erectile dysfunction (ED) has
emerged as a promising therapeutic approach. Aim To conduct the first double-blind …

[HTML][HTML] Erectile dysfunction in pelvic cancer survivors and current management options

J Bernal, K Venkatesan, FE Martins - Journal of Clinical Medicine, 2023 - mdpi.com
Pelvic malignancies, including prostate, rectal, and bladder cancers, are among the most
frequent malignancies found in the male population. These issues are most effectively and …

基于FAERS 数据库的4 种磷酸二酯酶5 抑制剂安全性分析

陈亚昆, 门鹏, 王攀 - 中国药物警戒, 2023 - zgywjj.magtechjournal.com
目的对真实世界不良事件报告数据进行挖掘, 分析4 种磷酸二酯酶5 (PDE5)
抑制剂的上市后安全性特征. 方法检索美国食品药品监督管理局(FDA) 不良事件报告系统 …

Safety of four phosphodiesterase 5 inhibitors based on the FAERS database

Y CHEN, P MEN, P WANG - Chinese Journal of …, 2023 - zgywjj.magtechjournal.com
Objective To mine real-world adverse event report data and analyze the post-marketing
safety characteristics of four phosphodiesterase 5 (PDE5) inhibitors. Methods By searching …