The industrial versatility of Gluconobacter oxydans: current applications and future perspectives

GAR da Silva, SSS Oliveira, SF Lima… - World Journal of …, 2022 - Springer
Gluconobacter oxydans is a well-known acetic acid bacterium that has long been applied in
the biotechnological industry. Its extraordinary capacity to oxidize a variety of sugars …

Comparative analysis of the chemical and biochemical synthesis of keto acids

Z Luo, S Yu, W Zeng, J Zhou - Biotechnology advances, 2021 - Elsevier
Keto acids are essential organic acids that are widely applied in pharmaceuticals,
cosmetics, food, beverages, and feed additives as well as chemical synthesis. Currently …

Microbial production of specialty organic acids from renewable and waste materials

S Alonso, M Rendueles, M Díaz - Critical reviews in biotechnology, 2015 - Taylor & Francis
Microbial production of organic acids has become a fast-moving field due to the increasing
role of these compounds as platform chemicals. In recent years, the portfolio of specialty …

Dissolved-oxygen feedback control fermentation for enhancing β-carotene in engineered Yarrowia lipolytica

PJ Lv, S Qiang, L Liu, CY Hu, YH Meng - Scientific reports, 2020 - nature.com
The DO-stat fed-batch fermentation was carried out to explore the volumetric productivity of β-
carotene in engineered Yarrowia lipolytica C11 strain. Using DO-stat fed-batch fermentation …

[HTML][HTML] The functional characterization of the 6-phosphogluconate dehydratase operon in 2-ketogluconic acid industrial producing strain Pseudomonas …

WJ Sun, QN Zhang, LL Li, MX Qu, XY Zan, FJ Cui… - Foods, 2024 - mdpi.com
Genus Pseudomonas bacteria mainly consume glucose through the Entner–Doudoroff (ED)
route due to a lack of a functional Embden–Meyerhof–Parnas (EMP) pathway. In the present …

Overexpression of membrane-bound gluconate-2-dehydrogenase to enhance the production of 2-keto-d-gluconic acid by Gluconobacter oxydans

K Li, X Mao, L Liu, J Lin, M Sun, D Wei, S Yang - Microbial Cell Factories, 2016 - Springer
Abstract Background 2-keto-d-gluconic acid (2KGA) is widely used as a chemical
intermediate in the cosmetic, pharmaceutical and environmental industries. Several …

Semi-continuous production of 2-keto-gluconic acid by Pseudomonas fluorescens AR4 from rice starch hydrolysate

WJ Sun, YZ Zhou, Q Zhou, FJ Cui, SL Yu, L Sun - Bioresource technology, 2012 - Elsevier
2-Keto-gluconic acid (2KGA) was produced in a semi-continuous process using
Pseudomonas fluorescens AR4 and rice starch hydrolysate (RSH). The bacterium was …

[HTML][HTML] Efficient biosynthesis of 2-keto-D-gluconic acid by fed-batch culture of metabolically engineered Gluconobacter japonicus

W Zeng, W Cai, L Liu, G Du, J Chen, J Zhou - Synthetic and Systems …, 2019 - Elsevier
keto-d-gluconic acid (2-KGA) is a key precursor for synthesising vitamin C and isovitamin C.
However, phage contamination is as constant problem in industrial production of 2-KGA …

2-Ketogluconic acid production by Klebsiella pneumoniae CGMCC 1.6366

D Wei, J Xu, J Sun, J Shi, J Hao - Journal of Industrial …, 2013 - academic.oup.com
Klebsiella pneumoniae CGMCC 1.6366 is a bacterium isolated for 1, 3-propanediol or 2, 3-
butanediol production previously. K. pneumoniae ΔbudA, a 2, 3-butanediol synthesis …

Two-Stage Semi-Continuous 2-Keto-Gluconic Acid (2KGA) Production by Pseudomonas plecoglossicida JUIM01 From Rice Starch Hydrolyzate

L Sun, DM Wang, WJ Sun, FJ Cui, JS Gong… - … in Bioengineering and …, 2020 - frontiersin.org
A two-stage semi-continuous strategy for producing 2-keto-gluconic acid (2KGA) by
Pseudomonas plecoglossicida JUIM01 from rice starch hydrolyzate (RSH) has been …