Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

Epigenetic regulatory mechanisms, including DNA methylation, histone modification,
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …

Abstract Translocator Protein 18 kDa (TSPO), previously named Peripheral Benzodiazepine
Receptor, is a well-validated and widely used biomarker of neuroinflammation to assess …

Depression is the most prevalent and debilitating mental disorder that affects a substantial
number of people globally, hindering all aspects of their lives and leading to a high number …

Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with few
pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial …

Neuroplasticity is a complex physiological process occurring in the brain for its entire life.
However, it is of particular importance in the case of central nervous system (CNS) …

Background Focused ultrasound (FUS) is a medical technology that non-invasively
stimulates the brain and has been applied in thermal ablation, blood–brain barrier (BBB) …

The neural stem cell niche is a key regulator participating in the maintenance, regeneration,
and repair of the brain. Within the niche neural stem cells (NSC) generate new neurons …

Two of the most common neurodegenerative disorders–Alzheimer's and Parkinson's
diseases–are characterized by synaptic dysfunction and degeneration that culminate in …

Autism spectrum disorder (ASD) is a cluster of heterogeneous neurodevelopmental
conditions with atypical social communication and repetitive sensory-motor behaviors. The …