Phage ImmunoPrecipitation Sequencing (PhIP-Seq): the promise of high throughput serology
Simple Summary Determining the exposure or infection history of a person to a multitude of
viruses is not an easy task. Typically, antibody tests detect antibodies against proteins …
viruses is not an easy task. Typically, antibody tests detect antibodies against proteins …
Importance, applications and features of assays measuring SARS-CoV-2 neutralizing antibodies
P Gattinger, A Ohradanova-Repic… - International Journal of …, 2023 - mdpi.com
More than three years ago, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) caused the unforeseen COVID-19 pandemic with millions of deaths. In the …
CoV-2) caused the unforeseen COVID-19 pandemic with millions of deaths. In the …
Detailed analysis of antibody responses to SARS-CoV-2 vaccination and infection in macaques
AC Willcox, K Sung, ME Garrett, JG Galloway… - PLoS …, 2022 - journals.plos.org
Macaques are a commonly used model for studying immunity to human viruses, including
for studies of SARS-CoV-2 infection and vaccination. However, it is unknown whether …
for studies of SARS-CoV-2 infection and vaccination. However, it is unknown whether …
A performance comparison of two (electro) chemiluminescence immunoassays for detection and quantitation of serum anti‐spike antibodies according to SARS‐CoV …
J Camacho, E Albert, J Zulaica… - Journal of Medical …, 2023 - Wiley Online Library
The information provided by SARS‐CoV‐2 spike (S)‐targeting immunoassays can be
instrumental in clinical‐decision making. We compared the performance of the Elecsys® …
instrumental in clinical‐decision making. We compared the performance of the Elecsys® …
Impact of SARS-CoV-2 spike mutations on its activation by TMPRSS2 and the alternative TMPRSS13 protease
A Stevaert, R Van Berwaer, C Mestdagh, J Vandeput… - Mbio, 2022 - Am Soc Microbiol
The continuous emergence of new variants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) urges better understanding of the functional motifs in the spike …
coronavirus 2 (SARS-CoV-2) urges better understanding of the functional motifs in the spike …
Potential association factors for developing effective peptide-based cancer vaccines
Peptide-based cancer vaccines have been shown to boost immune systems to kill tumor
cells in cancer patients. However, designing an effective T cell epitope peptide-based …
cells in cancer patients. However, designing an effective T cell epitope peptide-based …
phippery: a software suite for PhIP-Seq data analysis
JG Galloway, K Sung, SS Minot, ME Garrett… - …, 2023 - academic.oup.com
We present the phippery software suite for analyzing data from phage display methods that
use immunoprecipitation and deep sequencing to capture antibody binding to peptides …
use immunoprecipitation and deep sequencing to capture antibody binding to peptides …
Long-lasting neutralizing antibodies and T cell response after the third dose of mRNA anti-SARS-CoV-2 vaccine in multiple sclerosis
A Maglione, R Francese, I Arduino, R Rosso… - Frontiers in …, 2023 - frontiersin.org
Background and objectives Long lasting immune response to anti-SARS-CoV-2 vaccination
in people with Multiple Sclerosis (pwMS) is still largely unexplored. Our study aimed at …
in people with Multiple Sclerosis (pwMS) is still largely unexplored. Our study aimed at …
Passive immunization with equine RBD-specific Fab protects K18-hACE2-mice against Alpha or Beta variants of SARS-CoV-2
Emergence of variants of concern (VOC) during the COVID-19 pandemic has contributed to
the decreased efficacy of therapeutic monoclonal antibody treatments for severe cases of …
the decreased efficacy of therapeutic monoclonal antibody treatments for severe cases of …
Elevated binding and functional antibody responses to SARS-CoV-2 in infants versus mothers
CI Stoddard, K Sung, ZA Yaffe, H Weight… - Nature …, 2023 - nature.com
Infant antibody responses to viral infection can differ from those in adults. However, data on
the specificity and function of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
the specificity and function of severe acute respiratory syndrome coronavirus 2 (SARS-CoV …