Lysosomes are organelles involved in cell metabolism, waste degradation, and cellular
material circulation. They play a key role in the maintenance of cellular physiological …

Lysosomes have long been regarded as the “garbage dump” of the cell. More recently,
however, researchers have revealed novel roles for lysosomal membranes in autophagy …

The bioactivity of nanoparticles has engendered a promise in scientific communities for
developing novel therapeutic strategies. This study investigated the protective effects of …

The purpose of this meta-analysis was to evaluate the beneficial and adverse effects of
tripterygium glycosides (TGs) combined with angiotensin II receptor blocker (ARB) on …

In patients with diabetic kidney disease (DKD), plasma renin activity is usually decreased,
but there is limited information on urinary renin and its origin. Urinary renin was evaluated in …

The megalin/cubilin complex is responsible for the majority of serum protein reclamation in
the proximal tubules. The current study examined if decreases in their renal expression …

Aims/hypothesis Identifying rare coding variants associated with albuminuria may open new
avenues for preventing chronic kidney disease and end-stage renal disease, which are …

High salt diet (HSD) is a hallmark of blood pressure elevations, weight gain and diabetes
onset in the metabolic syndrome. In kidney, compensatory mechanisms are activated to …

This study investigated whether the coadministration of vitamin E (VitE) diminishes the
harmful effects provoked by plasticizer bisphenol S (BPS) in the serum metabolites related to …

Trials on cardiovascular and renal outcomes in patients with type 2 diabetes have
consistently demonstrated that sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce …