Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Cellular senescence is a state of irreversible cell cycle arrest associated with ageing.
Senescence of different cardiac cell types can direct the pathophysiology of cardiovascular …

Heart failure (HF) is a clinical syndrome that usually develops in the elderly. Complex
interactions of the cardiovascular aging process with risk factors (obesity, hypertension, and …

While the increased arrhythmic tendency during acute COVID-19 infection is recognised, the
long-term cardiac electrophysiological complications are less well known. There are a high …

Acute stress is a physiological condition that may induce several neural dysfunctions with a
significant impact on life quality. Accordingly, it would be important to monitor stress in …

Aging is a major risk factor for impaired cardiovascular health. Because the aging
myocardium is characterized by microcirculatory dysfunction, and because nerves align with …

Aging of the cardiovascular regulatory function manifests as an imbalance between the
sympathetic and parasympathetic (vagal) components of the autonomic nervous system …

Sphingosine 1-phosphate (S1P) receptor (S1PR) modulators have a complex mechanism of
action, which are among the most efficient therapeutic options in multiple sclerosis (MS) and …

During ageing molecular damage leads to the accumulation of several hallmarks of ageing
including mitochondrial dysfunction, cellular senescence, genetic instability and chronic …

Objective The aim of this study was to assess age-related changes in cardiac autonomic
modulation and heart rate variability (HRV) and their association with spontaneous and …