Eukaryotic cells contain membranes with various curvatures, from the near-plane plasma
membrane to the highly curved membranes of organelles, vesicles, and membrane …

The mechanisms by which peripheral membrane proteins generate curvature is currently an
active area of research. One of the proposed mechanisms is amphipathic insertion or the …

Membranes play essential roles in biological systems and are tremendously diverse in the
topologies and chemical and elastic properties that define their functions. In many cases, a …

Over the last few decades, the spatial organization of biomembranes has received a lot of
attention. With the fluid mosaic model, Singer and Nicolson proposed that biomembranes …

Membrane curvature is essential for many cellular structures and processes. Membrane
leaflet asymmetry, lipid composition, and proteins contribute to the generation, maintenance …

Structural and mechanical properties of membranes such as thickness, tail order, bending
modulus and curvature energetics play crucial role in controlling various cellular functions …

The precise spatiotemporal control of nanoscale membrane shape and composition is the
result of a complex interplay of individual and collective molecular behaviors. Here, we …

We describe methods to analyze lipid distributions and curvature in membranes with
complex lipid mixtures and embedded membrane proteins. We discuss issues involved in …

The epidermal growth factor receptor (EGFR) governs pivotal signaling pathways in cell
proliferation and survival, with mutations implicated in numerous cancers. The organization …

Molecular dynamics (MD) simulations are a useful tool when studying the properties of
membranes as they allow for a molecular view of lipid interactions with proteins, nucleic …