Millions of people are affected by respiratory diseases, leading to a significant health burden
globally. Because of the current insufficient knowledge of the underlying mechanisms that …

Introduction: Progressive lung disease is the major cause of morbidity and mortality in
patients with cystic fibrosis (CF). Methods of correctly predicting the future progression of …

Background The current diagnosis of infective endocarditis (IE) is based on the modified
Duke criteria, which has approximately 80% sensitivity for the diagnosis of native valve …

Aims To examine the utility of 18F-fluorodeoxyglucose positron emission
tomography/computed tomography (18F-FDG PET/CT) in the early diagnosis of cardiac …

Pulmonary exacerbations are important clinical events for cystic fibrosis (CF) patients.
Studies assessing the ability of the lung clearance index (LCI) to detect treatment response …

Background The dawn of precision medicine and CFTR modulators require more detailed
assessment of lung structure in cystic fibrosis (CF) clinical studies. Various imaging markers …

Inflammation is a common feature in several types of lung disease and is a frequent end
point to validate lung disease models, evaluate genetic or environmental impact on disease …

The ability to image inflammation in vivo can improve our understanding of the
pathophysiology underlying various disease etiologies, including cancer, atherosclerosis …

Infectious and inflammatory pulmonary diseases are a leading cause of morbidity and
mortality worldwide. Although infrequently used in this setting, molecular imaging may …

With the exception of radiolabeled monoclonal antibodies, antibody fragments and
radiolabeled peptides which have seen little application in the pediatric population, the …