Obesity: a review of pathophysiology and classification

B Busebee, W Ghusn, L Cifuentes, A Acosta - Mayo Clinic Proceedings, 2023 - Elsevier
Obesity is a chronic, multifactorial, and morbid disease. In the United States, 69% of adults
are overweight or have obesity, and the global prevalence of obesity is increasing. Obesity …

Phenotyping the obesities: reality or utopia?

P Portincasa, G Frühbeck - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
In this thematic issue on phenotyping the obesities, prominent international experts offer an
insightful and comprehensive collection of articles covering the current knowledge in the …

Precision medicine of obesity as an integral part of type 2 diabetes management–past, present, and future

L Szczerbinski, JC Florez - The Lancet Diabetes & Endocrinology, 2023 - thelancet.com
Obesity is a complex and heterogeneous condition that leads to various metabolic
complications, including type 2 diabetes. Unfortunately, for some, treatment options to date …

Effects of dietary fibre on metabolic health and obesity

EC Deehan, V Mocanu, KL Madsen - Nature Reviews Gastroenterology …, 2024 - nature.com
Obesity and metabolic syndrome represent a growing epidemic worldwide. Body weight is
regulated through complex interactions between hormonal, neural and metabolic pathways …

Type-2 diabetes mellitus remission prediction models after Roux-En-Y gastric bypass and sleeve gastrectomy based on disease severity scores

W Ghusn, K Hage, RA Vierkant… - Diabetes Research and …, 2024 - Elsevier
Aim Metabolic and bariatric surgery (MBS) is considered one of the most effective
interventions for weight loss and associated type-2 diabetes mellitus (T2DM) remission …

The melanocortin‐4 receptor pathway and the emergence of precision medicine in obesity management

S Fansa, A Acosta - Diabetes, Obesity and Metabolism, 2024 - Wiley Online Library
Over the past few decades, there has been a global surge in the prevalence of obesity,
rendering it a globally recognized epidemic. Contrary to simply being a medical condition …

Precision gestational diabetes treatment: a systematic review and meta-analyses

JL Benham, V Gingras, NM McLennan, J Most… - Communications …, 2023 - nature.com
Abstract Background Gestational Diabetes Mellitus (GDM) affects approximately 1 in 7
pregnancies globally. It is associated with short-and long-term risks for both mother and …

Maladaptive Eating Behaviours, Generalised Anxiety Disorder and Depression Severity: A Comparative Study between Adult Women with Overweight, Obesity, and …

T Witaszek, M Babicki, A Brytek-Matera… - Nutrients, 2023 - mdpi.com
(1) Background: Causes of obesity are multifactorial and include genetic predisposition as
well as behavioural, psychological, social, and hormonal influences. We aimed to compare …

Polymorphisms of fat mass and obesity-associated gene in the pathogenesis of child and adolescent metabolic syndrome

Y Song, H Wade, B Zhang, W Xu, R Wu, S Li, Q Su - Nutrients, 2023 - mdpi.com
Childhood metabolic syndrome (MetS) is prevalent around the world and is associated with
a high likelihood of suffering from severe diseases such as cardiovascular disease later in …

Poly-agonist pharmacotherapies for metabolic diseases: hopes and new challenges

C Allard, D Cota, C Quarta - Drugs, 2024 - Springer
The use of glucagon-like peptide-1 (GLP-1) receptor-based multi-agonists in the treatment of
type 2 diabetes and obesity holds great promise for improving glycaemic control and weight …