Regulatory mechanisms of somatostatin expression

E Ampofo, L Nalbach, MD Menger… - International journal of …, 2020 - mdpi.com
Somatostatin is a peptide hormone, which most commonly is produced by endocrine cells
and the central nervous system. In mammals, somatostatin originates from pre …

Structural and compositional diversity in the kainate receptor family

P Selvakumar, J Lee, N Khanra, C He, H Munguba… - Cell reports, 2021 - cell.com
The kainate receptors (KARs) are members of the ionotropic glutamate receptor family and
assemble into tetramers from a pool of five subunit types (GluK1–5). Each subunit confers …

Convergent dopamine and ALK4 signaling to PCBP1 controls FosB alternative splicing and cocaine behavioral sensitization

FA Krapacher, D Fernández‐Suárez… - The EMBO …, 2022 - embopress.org
ΔfosB is an alternatively spliced product of the FosB gene that is essential for dopamine‐
induced reward pathways and that acts as a master switch for addiction. However, the …

Activin receptor ALK4 promotes adipose tissue hyperplasia by suppressing differentiation of adipocyte precursors

ES Lee, T Guo, RK Srivastava, A Shabbir… - Journal of Biological …, 2023 - ASBMB
Adipocyte hyperplasia and hypertrophy are the two main processes contributing to adipose
tissue expansion, yet the mechanisms that regulate and balance their involvement in obesity …

Partial inhibition of activin receptor-like kinase 4 alleviates bladder fibrosis caused by bladder outlet obstruction

N Wang, L Lu, Q feng Cao, J Ding, C Wang… - Experimental Cell …, 2021 - Elsevier
The bladder undergoes profound structural alterations after bladder outlet obstruction
(BOO), characterized by hypertrophy of the bladder wall and accumulation of extracellular …

Dopamine and ALK4 signaling synergize to induce PCBP1-mediated alternative splicing of FosB and sustained behavioral sensitization to cocaine

FA Krapacher, D Fernández-Suárez, A Andersson… - bioRxiv, 2022 - biorxiv.org
ΔFosB, an alternative spliced product of FosB, is an essential component of dopamine-
induced reward pathways and a master switch for addiction. However, the molecular …

Role of Activin in Synaptic Plasticity of Mouse Hippocampus

M Dahlmanns - 2021 - search.proquest.com
Role of Activin in Synaptic Plasticity of Mouse Hippocampus Page 1 Role of Activin in Synaptic
Plasticity of Mouse Hippocampus Die Rolle von Activin bei der synaptischen Plastizität im …

[PDF][PDF] Molecular mechanisms regulating the maturation of cortical interneurons

M Moissidis - 2022 - kclpure.kcl.ac.uk
Mammalian cortical function relies on the intricate interplay between inhibitory interneurons
and excitatory pyramidal cells. Parvalbumin-expressing (PV) interneurons represent the …

The Impact of the Non-immune Chemiome on T Cell Activation

KM Rosenberg - 2020 - search.proquest.com
T cells are critical organizers of the immune response and rigid control over their activation
is necessary for balancing host defense and immunopathology. It takes 3 signals provided …