[HTML][HTML] Eccentric muscle contractions: risks and benefits

S Hody, JL Croisier, T Bury, B Rogister… - Frontiers in …, 2019 - frontiersin.org
Eccentric contractions, characterized by the lengthening of the muscle-tendon complex,
present several unique features compared with other types of contractions, which may lead …

Lengthening our perspective: morphological, cellular, and molecular responses to eccentric exercise

RD Hyldahl, MJ Hubal - Muscle & nerve, 2014 - Wiley Online Library
The response of skeletal muscle to unaccustomed eccentric exercise has been studied
widely, yet it is incompletely understood. This review is intended to provide an up‐to‐date …

Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

H Neelakantan, CR Brightwell, TG Graber… - Biochemical …, 2019 - Elsevier
Aging is accompanied by progressive declines in skeletal muscle mass and strength and
impaired regenerative capacity, predisposing older adults to debilitating age-related muscle …

A New Immuno-, Dystrophin-Deficient Model, the NSG-mdx4Cv Mouse, Provides Evidence for Functional Improvement Following Allogeneic Satellite Cell …

RW Arpke, R Darabi, TL Mader, Y Zhang, A Toyama… - Stem …, 2013 - academic.oup.com
Transplantation of a myogenic cell population into an immunodeficient recipient is an
excellent way of assessing the in vivo muscle-generating capacity of that cell population. To …

Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury

SJP Pratt, SB Shah, CW Ward, JP Kerr… - Cellular and Molecular …, 2015 - Springer
Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which
weakness, increased susceptibility to muscle injury, and inadequate repair underlie the …

Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration

L Xie, A Yin, AS Nichenko, AM Beedle… - The Journal of …, 2018 - Am Soc Clin Investig
The remarkable regeneration capability of skeletal muscle depends on the coordinated
proliferation and differentiation of satellite cells (SCs). The self-renewal of SCs is critical for …

Eccentric exercise in aging and diseased skeletal muscle: good or bad?

RM Lovering, SV Brooks - Journal of applied Physiology, 2014 - journals.physiology.org
Evidence is accumulating regarding the benefits of exercise in people who are more
susceptible to injury, such as the elderly, or those with a neuromuscular disease, for …

Deletion of estrogen receptor α in skeletal muscle results in impaired contractility in female mice

BC Collins, TL Mader, CA Cabelka… - Journal of applied …, 2018 - journals.physiology.org
Estradiol deficiency in females can result in skeletal muscle strength loss, and treatment with
estradiol mitigates the loss. There are three primary estrogen receptors (ERs), and estradiol …

Laminin-111 enriched fibrin hydrogels for skeletal muscle regeneration

M Marcinczyk, H Elmashhady, M Talovic, A Dunn… - Biomaterials, 2017 - Elsevier
Abstract Laminin (LM)-111 supplementation has improved muscle regeneration in several
models of disease and injury. This study investigated a novel hydrogel composed of …

Regenerative and rehabilitative medicine: a necessary synergy for functional recovery from volumetric muscle loss injury

SM Greising, CL Dearth, BT Corona - Cells Tissues Organs, 2016 - karger.com
Volumetric muscle loss (VML) is a complex and heterogeneous problem due to significant
traumatic or surgical loss of skeletal muscle tissue. The consequences of VML are …