Toxicology of deoxynivalenol and its acetylated and modified forms

D Payros, I Alassane-Kpembi, A Pierron, N Loiseau… - Archives of …, 2016 - Springer
Mycotoxins are the most frequently occurring natural contaminants in human and animal
diet. Among them, deoxynivalenol (DON), produced by Fusarium, is one of the most …

Risks to human and animal health related to the presence of deoxynivalenol and its acetylated and modified forms in food and feed

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2017 - Wiley Online Library
Deoxynivalenol (DON) is a mycotoxin primarily produced by Fusarium fungi, occurring
predominantly in cereal grains. Following the request of the European Commission, the …

Role of satiety hormones in anorexia induction by Trichothecene mycotoxins

C Terciolo, M Maresca, P Pinton, IP Oswald - Food and Chemical …, 2018 - Elsevier
The trichothecenes, produced by Fusarium, contaminate animal feed and human food in all
stages of production and lead to a large spectrum of adverse effects for animal and human …

Appropriateness to set a group health‐based guidance value for fumonisins and their modified forms

EFSA Panel on Contaminants in the Food Chain … - Efsa …, 2018 - Wiley Online Library
Abstract The EFSA Panel on Contaminants in the Food Chain (CONTAM) established a
tolerable daily intake (TDI) for fumonisin B1 (FB 1) of 1.0 μg/kg body weight (bw) per day …

A novel CCK receptor GPR173 mediates potentiation of GABAergic inhibition

L He, H Shi, G Zhang, Y Peng, A Ghosh… - Journal of …, 2023 - Soc Neuroscience
Cholecystokinin (CCK) enables excitatory circuit long-term potentiation (LTP). Here, we
investigated its involvement in the enhancement of inhibitory synapses. Activation of GABA …

[HTML][HTML] Combined exposure to deoxynivalenol facilitates lipid metabolism disorder in high-fat-diet-induced obesity mice

J Jin, B Huangfu, F Xing, W Xu, X He - Environment International, 2023 - Elsevier
Deoxynivalenol (DON) is a trichothecene toxin that mainly produced by strains of Fusarium
spp. DON contamination is widely distributed and is a global food safety threat. Existing …

Deoxynivalenol decreased intestinal immune function related to NF-κB and TOR signalling in juvenile grass carp (Ctenopharyngodon idella)

C Huang, L Feng, WD Jiang, P Wu, Y Liu… - Fish & shellfish …, 2019 - Elsevier
Deoxynivalenol (DON) is one of the most common mycotoxins in animal feed worldwide and
causes significant threats to the animal production. The intestine is an important mucosal …

Deoxynivalenol (vomitoxin)-induced cholecystokinin and glucagon-like peptide-1 release in the STC-1 enteroendocrine cell model is mediated by calcium-sensing …

HR Zhou, JJ Pestka - Toxicological Sciences, 2015 - academic.oup.com
Food refusal is a hallmark of exposure of experimental animals to the trichothecene
mycotoxin deoxynivalenol (DON), a common foodborne contaminant. Although studies in …

Comparison of anorectic potencies of type A trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol, and neosolaniol

J Zhang, H Zhang, S Liu, W Wu, H Zhang - Toxins, 2018 - mdpi.com
Trichothecene mycotoxins are common contaminants in cereal grains and negatively impact
human and animal health. Although anorexia is a common hallmark of type B trichothecenes …

Potential roles for calcium-sensing receptor (CaSR) and transient receptor potential ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol (vomitoxin)

W Wu, HR Zhou, JJ Pestka - Archives of toxicology, 2017 - Springer
Food contamination by the trichothecene mycotoxin deoxynivalenol (DON, vomitoxin) has
the potential to adversely affect animal and human health by suppressing food intake and …