[HTML][HTML] Biofilms by bacterial human pathogens: Clinical relevance-development, composition and regulation-therapeutical strategies

A Schulze, F Mitterer, JP Pombo, S Schild - Microbial Cell, 2021 - ncbi.nlm.nih.gov
Notably, bacterial biofilm formation is increasingly recognized as a passive virulence factor
facilitating many infectious disease processes. In this review we will focus on bacterial …

Searching for the secret of stickiness: how biofilms adhere to surfaces

Z Jiang, T Nero, S Mukherjee, R Olson… - Frontiers in …, 2021 - frontiersin.org
Bacterial biofilms are communities of cells enclosed in an extracellular polymeric matrix in
which cells adhere to each other and to foreign surfaces. The development of a biofilm is a …

Outer membrane vesicles of Vibrio cholerae protect and deliver active cholera toxin to host cells via porin-dependent uptake

FG Zingl, HB Thapa, M Scharf, P Kohl, AM Müller… - MBio, 2021 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are an emerging research field due to their multifactorial
composition and involvement in interspecies and intraspecies communication. Recent …

What are we missing by using hydrophilic enrichment? Improving bacterial glycoproteome coverage using total proteome and FAIMS analyses

AR Ahmad Izaham, CS Ang, S Nie… - Journal of Proteome …, 2020 - ACS Publications
Hydrophilic interaction liquid chromatography (HILIC) glycopeptide enrichment is an
indispensable tool for the high-throughput characterization of glycoproteomes. Despite its …

Identifying the targets and functions of N-linked protein glycosylation in Campylobacter jejuni

JA Cain, AL Dale, Z Sumer-Bayraktar, N Solis… - Molecular omics, 2020 - pubs.rsc.org
Campylobacter jejuni is a major cause of bacterial gastroenteritis in humans that is primarily
associated with the consumption of inadequately prepared poultry products, since the …

Using Vibrio natriegens for High-Yield Production of Challenging Expression Targets and for Protein Perdeuteration

N Mojica, F Kersten, M Montserrat-Canals… - Biochemistry, 2024 - ACS Publications
Production of soluble proteins is essential for structure/function studies; however, this
usually requires milligram amounts of protein, which can be difficult to obtain with traditional …

The activity of the quorum sensing regulator HapR is modulated by the bacterial extracellular vesicle (BEV)‐associated protein ObfA of Vibrio cholerae

SP Ebenberger, F Cakar, YC Chen… - Journal of …, 2024 - Wiley Online Library
Vibrio cholerae, a facultative human pathogen and causative agent of the severe diarrheal
disease cholera, transits between the human intestinal tract and aquatic reservoirs. Like …

Integrated mass spectrometry-based multi-omics for elucidating mechanisms of bacterial virulence

L Man, WP Klare, AL Dale, JA Cain… - Biochemical Society …, 2021 - portlandpress.com
Despite being considered the simplest form of life, bacteria remain enigmatic, particularly in
light of pathogenesis and evolving antimicrobial resistance. After three decades of …

Host stimuli and operator binding sites controlling protein interactions between virulence master regulator ToxR and ToxS in Vibrio cholerae

M Lembke, T Höfler, AN Walter, S Tutz… - Molecular …, 2020 - Wiley Online Library
Protein–protein interactions (PPIs) are key mechanisms in the maintenance of biological
regulatory networks. Herein, we characterize PPIs within ToxR and its co‐activator, ToxS, to …

[PDF][PDF] The crystal structure of CbpD clarifies substrate-specificity motifs in chitin-active lytic polysaccharide monooxygenases

CM Dade, B Douzi, C Cambillau, G Ball… - … Section D: Structural …, 2022 - journals.iucr.org
Pseudomonas aeruginosa secretes diverse proteins via its type 2 secretion system,
including a 39 kDa chitin-binding protein, CbpD. CbpD has recently been shown to be a lytic …