What is polypharmacy? A systematic review of definitions

N Masnoon, S Shakib, L Kalisch-Ellett, GE Caughey - BMC geriatrics, 2017 - Springer
Background Multimorbidity and the associated use of multiple medicines (polypharmacy), is
common in the older population. Despite this, there is no consensus definition for …

Hypertension management in older and frail older patients

A Benetos, M Petrovic, T Strandberg - Circulation research, 2019 - Am Heart Assoc
The prevalence of arterial hypertension, particularly systolic hypertension, is constantly
rising worldwide. This is mainly the clinical expression of arterial stiffening as a result of the …

Diretrizes brasileiras de hipertensão arterial–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
A HA tem alta prevalência e é um dos principais fatores de risco para as DCV e renais,
apresentando determinantes genéticos, ambientais e sociais combinados. Mostra-se de …

Brazilian guidelines of hypertension–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
SciELO - Brasil - Diretrizes Brasileiras de Hipertensão Arterial – 2020 Diretrizes Brasileiras de
Hipertensão Arterial – 2020 Acessibilidade / Reportar erro Brasil Lista alfabética de periódicos …

Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial

BP Halliday, R Wassall, AS Lota, Z Khalique… - The Lancet, 2019 - thelancet.com
Background Patients with dilated cardiomyopathy whose symptoms and cardiac function
have recovered often ask whether their medications can be stopped. The safety of …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

Polypharmacy: evaluating risks and deprescribing

AD Halli-Tierney, C Scarbrough, D Carroll - American family physician, 2019 - aafp.org
Polypharmacy, defined as regular use of at least five medications, is common in older adults
and younger at-risk populations and increases the risk of adverse medical outcomes. There …

The epidemiology of polypharmacy in older adults: register-based prospective cohort study

L Morin, K Johnell, ML Laroche, J Fastbom… - Clinical …, 2018 - Taylor & Francis
Objective Polypharmacy is the concomitant use of several drugs by a single person, and it
increases the risk of adverse drug-related events in older adults. Little is known about the …

Effect of a pharmacist-led educational intervention on inappropriate medication prescriptions in older adults: the D-PRESCRIBE randomized clinical trial

P Martin, R Tamblyn, A Benedetti, S Ahmed… - Jama, 2018 - jamanetwork.com
Importance High rates of inappropriate prescribing persist among older adults in many
outpatient settings, increasing the risk of adverse drug events and drug-related …

Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens

PA Rochon, M Petrovic, A Cherubini… - The Lancet Healthy …, 2021 - thelancet.com
Polypharmacy is very common in older adults and increases the risk of inappropriate and
unsafe prescribing for older adults. Older adults, particularly women (who make up the …