Effect of airway wall motion on particle deposition and delivery in the neonatal trachea

CC Gunatilaka, C McKenzie, Q Xiao, NS Higano… - Journal of Aerosol …, 2024 - Elsevier
Modeling pulmonary drug delivery in the airway using computational fluid dynamics (CFD)
simulations tracks drug particles throughout the airway, providing valuable information on …

Pulmonary function of children with tracheomalacia and associated clinical factors

W Boonjindasup, JM Marchant… - Pediatric …, 2022 - Wiley Online Library
Objectives Spirometry is easily accessible yet there is limited data in children with
tracheomalacia. Availability of such data may inform clinical practice. We aimed to describe …

Tracheomalacia reduces aerosolized drug delivery to the lung

CC Gunatilaka, C McKenzie, EB Hysinger… - Journal of Aerosol …, 2024 - liebertpub.com
Rationale: Neonates with respiratory issues are frequently treated with aerosolized
medications to manage lung disease or facilitate airway clearance. Dynamic tracheal …

[HTML][HTML] Scale resolving simulations of the effect of glottis motion and the laryngeal jet on flow dynamics during respiration

J Emmerling, S Vahaji, DAV Morton, DF Fletcher… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective The movement of the respiratory walls has a significant
impact on airflow through the respiratory tract. The majority of computational fluid dynamics …

Comparison of weighting algorithms to mitigate respiratory motion in free-breathing neonatal pulmonary radial UTE-MRI

DB Gandhi, NS Higano, AD Hahn… - Biomedical Physics …, 2024 - iopscience.iop.org
Background. Thoracoabdominal MRI is limited by respiratory motion, especially in
populations who cannot perform breath-holds. One approach for reducing motion blurring in …

Predicting tracheal work of breathing in neonates based on radiological and pulmonary measurements

CC Gunatilaka, EB Hysinger, A Schuh… - Journal of Applied …, 2022 - journals.physiology.org
Tracheomalacia is an airway condition in which the trachea excessively collapses during
breathing. Neonates diagnosed with tracheomalacia require more energy to breathe, and …

Diagnostic Approach to Tracheomalacia and Medical Management

EB Hysinger, SM Zak - Pediatric Aerodigestive Medicine: An …, 2024 - Springer
Tracheomalacia is the dynamic collapse of the trachea during the respiratory cycle. It is
common in children due to ongoing development of the trachea and differences in the …

[PDF][PDF] Improving the Utility and Understanding of Lung Function Tests in Children

W Boonjindasup - 2024 - researchers.cdu.edu.au
Respiratory diseases are among the most common health problems globally and many have
their origins in childhood, such as asthma, bronchiectasis and chronic obstructive pulmonary …

[PDF][PDF] Pulmonary function of children with tracheomalacia and associated clinical factors

MD Wicharn Boonjindasup, RJT MD - 2022 - ris.cdu.edu.au
Objectives: Spirometry is easily accessible yet there is limited data in children with
tracheomalacia. Availability of such data may inform clinical practice. We aimed to describe …