Brain connectivity in neurodegenerative diseases—from phenotype to proteinopathy
Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …
Transcranial magnetic stimulation and amyotrophic lateral sclerosis: pathophysiological insights
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder of
the motor neurons in the motor cortex, brainstem and spinal cord. A combination of upper …
the motor neurons in the motor cortex, brainstem and spinal cord. A combination of upper …
[HTML][HTML] Complex Pearson correlation coefficient for EEG connectivity analysis
In the background of all human thinking—acting and reacting are sets of connections
between different neurons or groups of neurons. We studied and evaluated these …
between different neurons or groups of neurons. We studied and evaluated these …
[HTML][HTML] Advanced diffusion MRI fiber tracking in neurosurgical and neurodegenerative disorders and neuroanatomical studies: a review
Diffusion MRI enabled in vivo microstructural imaging of the fiber tracts in the brain resulting
in its application in a wide range of settings, including in neurological and neurosurgical …
in its application in a wide range of settings, including in neurological and neurosurgical …
Structural brain network imaging shows expanding disconnection of the motor system in amyotrophic lateral sclerosis
E Verstraete, JH Veldink, LH van den Berg… - Human brain …, 2014 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative disease, which primarily
targets the motor system. The structural integrity of the motor network and the way it is …
targets the motor system. The structural integrity of the motor network and the way it is …
Genetic architecture of the white matter connectome of the human brain
White matter tracts form the structural basis of large-scale brain networks. We applied brain-
wide tractography to diffusion images from 30,810 adults (UK Biobank) and found significant …
wide tractography to diffusion images from 30,810 adults (UK Biobank) and found significant …
Neuroimaging in amyotrophic lateral sclerosis
The catastrophic system failure in amyotrophic lateral sclerosis is characterized by
progressive neurodegeneration within the corticospinal tracts, brainstem nuclei and spinal …
progressive neurodegeneration within the corticospinal tracts, brainstem nuclei and spinal …
Correlation between structural and functional connectivity impairment in amyotrophic lateral sclerosis
R Schmidt, E Verstraete, MA de Reus… - Human brain …, 2014 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by
progressive loss of motor function. While the pathogenesis of ALS remains largely unknown …
progressive loss of motor function. While the pathogenesis of ALS remains largely unknown …
Statistical machine learning to identify traumatic brain injury (TBI) from structural disconnections of white matter networks
Identifying diffuse axonal injury (DAI) in patients with traumatic brain injury (TBI) presenting
with normal appearing radiological MRI presents a significant challenge. Neuroimaging …
with normal appearing radiological MRI presents a significant challenge. Neuroimaging …
[HTML][HTML] Imaging biomarkers for the diagnosis and prognosis of neurodegenerative diseases. The example of amyotrophic lateral sclerosis
M Mazón, JF Vázquez Costa, A Ten-Esteve… - Frontiers in …, 2018 - frontiersin.org
The term amyotrophic lateral sclerosis (ALS) comprises a heterogeneous group of fatal
neurodegenerative disorders of largely unknown etiology characterized by the upper motor …
neurodegenerative disorders of largely unknown etiology characterized by the upper motor …