Colorectal cancer (CRC) is the third most common cancer and has a high metastasis and
reoccurrence rate. Long noncoding RNAs (lncRNAs) play an important role in CRC growth …

Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

Glioblastoma (GBM) is an aggressive central nervous system cancer with a dismal
prognosis. The standard of care involves surgical resection followed by radiotherapy and …

Glioblastoma multiforme is the most common and aggressive primary brain tumor. Even with
aggressive treatment including surgical resection, radiation, and chemotherapy, patient …

The application of peptide drugs in cancer therapy is impeded by their poor biostability and
weak cell permeability. Therefore, it is imperative to find biostable and cell-permeable …

The high mortality rates of cancer patients receiving standard treatments emphasize the
crucial need for alternative treatments. One promising strategy is to use organic …

Gene therapy has great potential to treat a range of different diseases, such as cancer. For
that therapeutic gene can be inserted into a plasmid vector and delivered specifically to …

The treatment of glioma is one of the most challenging tasks in clinic. As an intracranial
tumor, glioma exhibits many distinctive characteristics from other tumors. In particular …

Cell penetrating peptides (CPPs) were widely used for drug delivery to tumor. However, the
nonselective in vivo penetration greatly limited the application of CPPs-mediated drug …

The application of tumor targeting ligands to the treatment of cancer holds promise for
improving efficacy and reducing toxicity. L T7 (L (HAIYPRH)) peptide, a phage display …