Bacteria use quorum sensing to orchestrate gene expression programmes that underlie
collective behaviours. Quorum sensing relies on the production, release, detection and …

Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …

Hydrogels with high mechanical strength and injectability have attracted extensive attention
in biomedical and tissue engineering. However, endowing a hydrogel with both properties is …

The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …

The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that
regulates many bacterial behaviors and is of key importance for driving the lifestyle switch …

In many prokaryotes, type III clustered regularly interspaced short palindromic repeat
(CRISPR)–CRISPR-associated (Cas) systems detect and degrade invasive genetic …

Formation of biofilm is a survival strategy for bacteria and fungi to adapt to their living
environment, especially in the hostile environment. Under the protection of biofilm, microbial …

Biofilms are communities of microorganisms that are attached to a surface and play a
significant role in the persistence of bacterial infections. Bacteria within a biofilm are several …

Biofilm formation and biofilm-induced biodeterioration of surfaces have deeply affected the
life of our community. Cyclic dimeric guanosine monophosphate (c-di-GMP) is a small …

Caries and periodontitis are the two most common human dental diseases and are caused
by dysbiosis of oral flora. Although commensal microorganisms have been demonstrated to …