Autologous bone graft is considered as the gold standard in bone reconstructive surgery.
However, the quantity of bone available is limited and the harvesting procedure requires a …

Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

Bone is formed by a series of complex events involving the mineralization of extracellular
matrix proteins rigidly orchestrated by cells with specific functions of maintaining the integrity …

Background Tissue engineering (TE) is the main approach for stimulating the body's
mechanisms to regenerate damaged or diseased organs. Bone and cartilage tissues due to …

In adults and children over two years of age, large cranial defects do not reossify
successfully, posing a substantial biomedical burden. The osteogenic potential of bone …

As life expectancy increases, malfunction or loss of tissue caused by injury or disease leads
to reduced quality of life in many patients at significant socioeconomic cost. Even though …

Biphasic, triphasic and multiphasic (polyphasic) calcium orthophosphates have been sought
as biomaterials for reconstruction of bone defects in maxillofacial, dental and orthopedic …

The promise of cellular therapy lies in the repair of damaged organs and tissues in vivo as
well as generating tissue constructs in vitro for subsequent transplantation. Unfortunately …

We report the effects of two-dimensional graphene nanostructures; graphene nano-onions
(GNOs), graphene oxide nanoribbons (GONRs), and graphene oxide nanoplatelets …

Due to the chemical similarity to the inorganic constituents of calcified tissues of mammals,
biologically relevant calcium orthophosphates (CaPO 4) have been applied as artificial …