Treatable traits in pre‐COPD: Time to extend the treatable traits paradigm beyond established disease

SC Dharmage, R Faner, A Agustí - Respirology, 2024 - Wiley Online Library
To date, the treatable traits (TTs) approach has been applied in the context of managing
diagnosed diseases. TTs are clinical characteristics and risk factors that can be identified …

Diagnosis of Post-Hematopoietic Stem Cell Transplantation Bronchiolitis Obliterans Syndrome in Children: Time for a Rethink?

S Shanthikumar, WA Gower, KR Cooke… - … and Cellular Therapy, 2024 - Elsevier
Hematopoietic stem cell transplantation (HSCT) is undertaken in children with the aim of
curing a range of malignant and nonmalignant conditions. Unfortunately, pulmonary …

Effect of Cigarette Smoking on Clinical and Molecular Endpoints in COPD Patients

P Russo, F Milani, A De Iure, S Proietti… - International Journal of …, 2024 - mdpi.com
Cigarette smoking is a primary contributor to mortality risks and is associated with various
diseases. Among these, COPD represents a significant contributor to global mortality and …

Early Life Exposures and the Development of COPD Across the Life Course

NS Hopkinson, A Bush, JP Allinson… - American Journal of …, 2024 - atsjournals.org
There is growing recognition that various forms of deprivation, in particular adverse
antenatal or early life exposures, increase the risk of lung disease, in particular COPD …

Contemporary Concise Review 2023: Asthma

J Politis, PG Bardin, P Leong - Respirology (Carlton, Vic.), 2024 - pubmed.ncbi.nlm.nih.gov
Asthma research and management needs to meet the priorities of the end user-patients,
carers and clinicians. A better understanding of the natural history of asthma and the …

Asthma Inception: Epidemiologic Risk Factors and Natural History Across the Life-Course

E Melén, HJ Zar, V Siroux, D Shaw… - American Journal of …, 2024 - atsjournals.org
Asthma is a descriptive label for an obstructive, inflammatory disease in the lower airways
manifesting with symptoms including breathlessness, cough, difficulty in breathing and …

Lung function trajectories from school age to adulthood and their relationship with markers of cardiovascular disease risk

R Granell, S Haider, M Deliu, A Ullah, O Mahmoud… - thorax, 2024 - thorax.bmj.com
Rationale Lung function in early adulthood is associated with subsequent adverse health
outcomes. Objectives To ascertain whether stable and reproducible lung function …

Respiratory rescue is the new frontier

S Ranganathan - Thorax, 2024 - thorax.bmj.com
The cost of delivering healthcare is increasing in many countries, while at the same time,
populations are ageing and fertility rates falling. These factors are pushing policy-makers to …

Reinforcing the benefits of children's physical activity on lung health

G Wang, E Melén - Thorax, 2024 - thorax.bmj.com
Lung development starts already in utero whereas lung function development can be
conceived to begin shortly after birth, marked by the infant's first cry. This development …

Lifetime lung function trajectories: insights into risk factors, consequences and implications

DS Bui, NS Idrose, SC Dharmage - Thorax, 2024 - thorax.bmj.com
Maintaining optimal lung function throughout life is important not only for respiratory health
but also for overall health and longevity. With emerging evidence on the clinical significance …