Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

[HTML][HTML] Medicinal leech therapy—an overall perspective

AK Sig, M Guney, AU Guclu, E Ozmen - Integrative medicine research, 2017 - Elsevier
Complementary medicine methods have a long history, but modern medicine has just
recently focused on their possible modes of action. Medicinal leech therapy (MLT) or …

Whole genome analysis of a schistosomiasis-transmitting freshwater snail

CM Adema, LDW Hillier, CS Jones, ES Loker… - Nature …, 2017 - nature.com
Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …

Antimicrobial peptides and copper (II) ions: Novel therapeutic opportunities

J Portelinha, SS Duay, SI Yu, K Heilemann… - Chemical …, 2021 - ACS Publications
The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

Anionic antimicrobial peptides from eukaryotic organisms

F Harris, SR Dennison… - Current Protein and …, 2009 - ingentaconnect.com
Anionic antimicrobial peptides/proteins (AAMPs) were first reported in the early 1980s and
since then, have been established as an important part of the innate immune systems of …

Knowing your friends: invertebrate innate immunity fosters beneficial bacterial symbioses

SV Nyholm, J Graf - Nature Reviews Microbiology, 2012 - nature.com
The innate immune system is present in all animals and is a crucial first line of defence
against pathogens. However, animals also harbour large numbers of beneficial …

An updated molecular basis for mussel immunity

M Gerdol, P Venier - Fish & shellfish immunology, 2015 - Elsevier
Non-self recognition with the consequent tolerance or immune reaction is a crucial process
to succeed as living organisms. At the same time the interactions between host species and …

Antimicrobial peptides from marine invertebrates as a new frontier for microbial infection control

AJ Otero‐Gonzáiez, BS Magalhaes… - The FASEB …, 2010 - Wiley Online Library
Antimicrobial peptides are widely expressed in organisms and have been linked to innate
and acquired immunities in vertebrates. These compounds are constitutively expressed and …

Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence

TCG Bosch, R Augustin, F Anton-Erxleben… - Developmental & …, 2009 - Elsevier
Although many properties of the innate immune system are shared among multicellular
animals, the evolutionary origin remains poorly understood. Here we characterize the innate …

AniAMPpred: artificial intelligence guided discovery of novel antimicrobial peptides in animal kingdom

R Sharma, S Shrivastava, S Kumar Singh… - Briefings in …, 2021 - academic.oup.com
With advancements in genomics, there has been substantial reduction in the cost and time
of genome sequencing and has resulted in lot of data in genome databases. Antimicrobial …