The vitamin D receptor (VDR), in addition to other nuclear receptors, the pregnane X
receptor (PXR) and constitutive androstane receptor (CAR), is involved in the regulation of …

Vitamin D is both a vitamin and a hormone. It has pleotropic actions that extend beyond
calcium and phosphate homeostasis, regulation of parathyroid hormone, and the prevention …

Background Clinical studies indicate that vitamin D receptor (VDR) expression is reduced in
primary biliary cirrhosis patient livers. However, the mechanism by which activated VDR …

The compound 1α, 25-Dihydroxyvitamin D3 (1, 25 (OH) 2D3) is the active form of vitamin D3
and a representative ligand of the vitamin D receptor (VDR). Previous studies have …

Dedifferentiation has been identified as one of the causes of β-cell failure resulting in type 2
diabetes (T2D). This study tested whether increasing vitamin D receptor (VDR) expression …

Evidence in the literature suggests that 1α, 25-dihydroxyvitamin D 3 [1, 25 (OH) 2 D 3], the
vitamin D receptor ligand, down-regulated the expression of the rat renal organic anion …

Vitamin D3 and the synthetic vitamin D analogs, 1α‐hydroxyvitamin D3 [1α (OH) D3], 1α‐
hydroxyvitamin D2 [1α (OH) D2] and 25‐hydroxyvitamin D3 [25 (OH) D3] were appraised for …

The vitamin D‐deficient model, established in the C57BL/6 mouse after 8 weeks of feeding
vitamin D‐deficient diets in the absence or presence of added calcium, was found …

In order to improve calcium and phosphorus balance, beef cattle and dairy cows can be
supplemented with vitamin D. However, different vitamin D metabolites have been shown to …

Vitamin D is involved in retaining the balance of several minerals in the body, such as
calcium and phosphate, which are crucial for the bone formation and development. These …