Stem cell therapy in liver regeneration: Focus on mesenchymal stem cells and induced pluripotent stem cells
L Zhang, YY Fei, HT Han, J Xu, L Cheng, X Li - Pharmacology & …, 2022 - Elsevier
The liver has the ability to repair itself after injury; however, a variety of pathological changes
in the liver can affect its ability to regenerate, and this could lead to liver failure …
in the liver can affect its ability to regenerate, and this could lead to liver failure …
Reprogramming of tissue metabolism during cancer metastasis
K Ganguly, AC Kimmelman - Trends in cancer, 2023 - cell.com
Cancer is a systemic disease that involves malignant cell-intrinsic and-extrinsic metabolic
adaptations. Most studies have tended to focus on elucidating the metabolic vulnerabilities …
adaptations. Most studies have tended to focus on elucidating the metabolic vulnerabilities …
HDAC4 in cancer: A multitasking platform to drive not only epigenetic modifications
E Cuttini, C Goi, E Pellarin, R Vida… - Frontiers in molecular …, 2023 - frontiersin.org
Controlling access to genomic information and maintaining its stability are key aspects of
cell life. Histone acetylation is a reversible epigenetic modification that allows access to DNA …
cell life. Histone acetylation is a reversible epigenetic modification that allows access to DNA …
Dynamics of hepatocyte-cholangiocyte cell-fate decisions during liver development and regeneration
The immense regenerative potential of the liver is attributed to the ability of its two key cell
types–hepatocytes and cholangiocytes–to trans-differentiate to one another either directly or …
types–hepatocytes and cholangiocytes–to trans-differentiate to one another either directly or …
DNA methylation in cell plasticity and malignant transformation in liver diseases
M Kim, E Delgado, S Ko - Pharmacology & therapeutics, 2023 - Elsevier
The liver possesses extraordinary regenerative capacity mainly attributable to the ability of
hepatocytes (HCs) and biliary epithelial cells (BECs) to self-replicate. This ability is left over …
hepatocytes (HCs) and biliary epithelial cells (BECs) to self-replicate. This ability is left over …
Newer mitochondrial dynamics and their role of calcium signalling in liver regeneration
O Bedi, V Sapra, M Kumar, P Krishan - Mitochondrion, 2024 - Elsevier
Liver regeneration is a crucial process involved in cellular proliferation, differentiation, and
tissue repair. Calcium signaling impact key pathways like hepatocyte growth factor-Met …
tissue repair. Calcium signaling impact key pathways like hepatocyte growth factor-Met …
The influence of tissue spatial geometry and functional organisation on liver regeneration
L Aloia - Seminars in cell & developmental biology, 2022 - Elsevier
The adult liver exerts crucial functions, including nutrient metabolism and storage, bile
production and drug detoxification. These complex functions expose the liver to constant …
production and drug detoxification. These complex functions expose the liver to constant …
[HTML][HTML] miRNA-27a-3p is involved in the plasticity of differentiated hepatocytes
D Salerno, G Peruzzi, GR Pascucci, M Levrero… - Gene, 2024 - Elsevier
Background Epigenetic mechanisms, including DNA methylation, histone modifications, and
chromatin remodeling, are highly involved in the regulation of hepatocyte viability …
chromatin remodeling, are highly involved in the regulation of hepatocyte viability …
Epigenetic-based antioxidant effect of an ethanolic extract of Corylus avellana L. on THLE-2 human primary hepatocytes
B Benassi, L Bacchetta, O Maccioni… - Natural Product …, 2023 - Taylor & Francis
The ethanolic extract of Corylus avellana L hazelnut, prepared in our laboratories, has been
previously characterized by liquid chromatography coupled to high resolution mass …
previously characterized by liquid chromatography coupled to high resolution mass …
Quantifying tissue response after intraovarian platelet-rich plasma: Experimental approach to assess NF-κB and TNF-α as mediators to reduce local entropy
ES Sills - 2023 - preprints.org
Diminished ovarian reserve can be regarded as a sentinel indicator to foreshadow severe
follicular loss and, ultimately, systemic aging. The negative slope of human ovulatory fidelity …
follicular loss and, ultimately, systemic aging. The negative slope of human ovulatory fidelity …