Simple Summary In patients with stage III colon cancer, adjuvant chemotherapy with a
fluoropyrimidine combined with oxaliplatin reduces the risk of recurrence and mortality, with …

Background The prognostic value of perineural invasion (PNI) in colorectal cancer (CRC)
does not reach a consensus. Methods A comprehensive literature search for relevant reports …

Lymph node metastasis is regarded as an indubitable prognostic factor for predicting
disease recurrence and survival in patients with colorectal cancer. Lymph node status based …

Simple Summary Stage II colon cancer is defined as an early stage of the tumor disease,
without the involvement of lymph nodes or distant organs. In this group of patients, surgery …

Purpose Neoadjuvant chemotherapy is being actively tested as an emerging alternative for
the treatment of locally advanced colon cancer (LACC) patients, resembling its use in other …

The gradient monotonicity of existing tumor, node, metastases staging systems for colorectal
cancer is unsatisfactory. Our proposed T-plus staging system strengthens weighting of the T …

Background Accurate estimation of the long-term risk of recurrence in patients with non-
metastatic colorectal cancer (CRC) is crucial for clinical management. Histology-based deep …

Background: The incidence of colorectal cancer in patients younger than 50 years has been
increasing in recent years. Objective: Develop and validate prognostic nomograms …

Importance The addition of oxaliplatin to the standard 6-month fluorouracil-based adjuvant
chemotherapy in stage II colorectal cancer has been reported to reduce the risk of relapse …

Immune checkpoint inhibitors currently serve an important role in prolonging patients' overall
survival. However, the prognostic signatures of immune checkpoint inhibitors in colorectal …