Importance New data and therapeutic options warrant updated recommendations for the use
of antiretroviral drugs (ARVs) to treat or to prevent HIV infection in adults. Objective To …

Background Contemporary antiretroviral therapies (ART) and management strategies have
diminished both human immunodeficiency virus (HIV) treatment failure and the acquired …

The early period of infection with human immunodeficiency virus (HIV) has been associated
with higher infectiousness and, consequently, with more transmission events. Over the last …

Early treatment, soon after infection, reduces HIV transmissions and benefits patients. The
Transmission Reduction Intervention Project (TRIP) evaluated a network intervention to …

HIV continues to spread among vulnerable heterosexual (HET), Men-having-Sex with Men
(MSM) and intravenous drug user (IDU) populations, influenced by a complex array of …

Study design Study RV254/SEARCH 010 is a prospective cohort study conducted in
Bangkok, Thailand, which enrols predominantly Thai participants in the earliest stages of …

Understanding the determinants of broadly neutralizing antibody (bNAb) evolution is crucial
for the development of bNAb-based HIV vaccines. Despite emerging information on …

Introduction Providing HIV healthcare and Treatment as Prevention both depend on
diagnosing HIV cases, preferably soon after initial infection. We hypothesized that tracing …

Background Human immunodeficiency virus type 1 (HIV-1) genetic diversity increases over
the course of infection and can be used to infer the time since infection and, consequently …

This study reconstructed molecular networks of human immunodeficiency virus (HIV)
transmission history in an area affected by an epidemic of multiple HIV-1 subtypes and …