Airway smooth muscle in the pathophysiology and treatment of asthma
DC Doeing, J Solway - Journal of applied physiology, 2013 - journals.physiology.org
Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is
responsible for acute bronchoconstriction, which is potentiated by constrictor …
responsible for acute bronchoconstriction, which is potentiated by constrictor …
Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults
MC Dombret, K Alagha, LP Boulet… - European …, 2014 - Eur Respiratory Soc
Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit
for long-term asthma control outweighs the short-term risk of deterioration and …
for long-term asthma control outweighs the short-term risk of deterioration and …
[HTML][HTML] Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma
N Facciolongo, A Di Stefano, V Pietrini… - BMC pulmonary …, 2018 - Springer
Background Bronchial thermoplasty (BT) is a non-pharmacological intervention for severe
asthma whose mechanism of action is not completely explained by a reduction of airway …
asthma whose mechanism of action is not completely explained by a reduction of airway …
Transient receptor potential cation channel subfamily V (TRPV) and its importance in asthma.
J Reyes-García, A Carbajal-Garcia… - European journal of …, 2022 - Elsevier
Transient receptor potential (TRP) ion channels play critical roles in physiological and
pathological conditions. Increasing evidence has unveiled the contribution of TRP vanilloid …
pathological conditions. Increasing evidence has unveiled the contribution of TRP vanilloid …
[HTML][HTML] In vitro, in silico and in vivo study challenges the impact of bronchial thermoplasty on acute airway smooth muscle mass loss
IL Chernyavsky, RJ Russell… - European …, 2018 - Eur Respiratory Soc
Bronchial thermoplasty is a treatment for asthma. It is currently unclear whether its
histopathological impact is sufficiently explained by the proportion of airway wall that is …
histopathological impact is sufficiently explained by the proportion of airway wall that is …
Long-term modulation of airway remodelling in severe asthma following bronchial thermoplasty
N Jendzjowsky, A Laing, M Malig… - European …, 2022 - Eur Respiratory Soc
Rationale Bronchial thermoplasty is a mechanical therapeutic intervention that has been
advocated as an effective treatment option for severe asthma. The mechanism is promoted …
advocated as an effective treatment option for severe asthma. The mechanism is promoted …
[HTML][HTML] Emerging understanding of the mechanism of action of bronchial thermoplasty in asthma
JNS d'Hooghe, NHT Ten Hacken, EJM Weersink… - Pharmacology & …, 2018 - Elsevier
Bronchial Thermoplasty (BT) is an endoscopic treatment for moderate-to-severe asthma
patients who are uncontrolled despite optimal medical therapy. Effectiveness of BT has been …
patients who are uncontrolled despite optimal medical therapy. Effectiveness of BT has been …
Recent developments in bronchial thermoplasty for severe asthma
NC Thomson - Journal of asthma and allergy, 2019 - Taylor & Francis
Purpose Bronchial thermoplasty is approved in many countries worldwide as a non-
pharmacological treatment for severe asthma. This review summarizes recent publications …
pharmacological treatment for severe asthma. This review summarizes recent publications …
Quantitative CT detects changes in airway dimensions and air-trapping after bronchial thermoplasty for severe asthma
P Konietzke, O Weinheimer, MO Wielpütz… - European journal of …, 2018 - Elsevier
Objectives Bronchial thermoplasty (BT) can be considered in the treatment of severe asthma
to reduce airway smooth muscle mass and bronchoconstriction. We hypothesized that BT …
to reduce airway smooth muscle mass and bronchoconstriction. We hypothesized that BT …
Bronchial thermoplasty for severe asthma
Bronchial thermoplasty (BT) is a novel treatment of patients with severe asthma who
continue to be symptomatic despite maximal medical treatment. It aims to reduce the smooth …
continue to be symptomatic despite maximal medical treatment. It aims to reduce the smooth …