A myriad of environmental and genetic factors, as well as the physiologic process of aging,
contribute to Alzheimer's disease (AD) pathology. Neuroinflammation is and has been a …

Background: Amniotic Fluid Derived Mesenchymal Stem Cells (AF-MSCs) are adult,
fibroblast-like, self-renewable, multipotent stem cells. During the last decade, the therapeutic …

The integration of cell extrinsic and intrinsic signals is required to maintain appropriate cell
physiology and homeostasis. Bone morphogenetic proteins (BMPs) are cytokines that …

Alzheimer's disease, a progressive neurodegenerative disease, affects learning and
memory resulting from cholinergic dysfunction. Scopolamine has been employed to induce …

Melatonin, a highly lipophilic molecule secreted by the pineal gland in the brain, plays a role
in various biological functions. Previous studies reported that melatonin exerts its effect on …

Barckground Alzheimer's disease (AD) is mainly caused by cellular loss and dysfunction of
the basal forebrain cholinergic neurons and cholinergic axons in the cortex leading to slowly …

Background: The current work investigated the effect of melatonin on differentiation of
adipose mesenchymal stem cells (AD-MSCs) into dopamine producing cells and its effect on …

Amniotic fluid (AF) contains a heterogeneous population of cells that have been identified to
possess pluripotent and progenitor-like characteristics. These cells have been applied in …

Recent genome-wide association studies have introduced several genetic variants which
contribute to the late-onset Alzheimer's disease (LOAD). Polymorphisms of CHAT, TOMM40 …

In recent years, great interest has been devoted to finding alternative sources for human
stem cells which can be easily isolated, ideally without raising ethical objections. These …