The review focuses on acetylcholinesterase (AChE) inhibition of extracts and compounds
from southern African plants. We provide a detailed inventory of southern African plants …

Covering: July 2015 to June 2017. Previous review: Nat. Prod. Rep., 2016, 33, 1318–1343
Recent progress on the isolation, identification, biological activity and synthetic studies of the …

Mood disorders can be considered among the most common and debilitating mental
disorders. Major depression, as an example of mood disorders, is known to severely reduce …

Walnut (Juglans regia L.) septum represents an interesting bioactive compound source by-
product. In our study, a rich phenolic walnut septum extract, previously selected, was further …

It was recently shown that the gut microbiota of both depression patients and depression
model animals is significantly altered, suggesting that gut microbes are closely related to …

Asymmetric total synthesis of (−)-sila-mesembranol, the silicon analog of the natural alkaloid
(−)-mesembranol has been achieved in 3.3% yield over 11 steps. The chiral silicon center …

Sexual enhancers increase sexual potency, sexual pleasure, or libido. Substances
increasing libido alter the concentrations of specific neurotransmitters or sex hormones in …

An optimized ultrasound-assisted extractive method was developed to obtain a polyphenol-
enriched extract from the aerial parts of Thymus comosus Heuff. ex Griseb. et Schenk …

Globally, the search for safe and potent natural-based treatment for depression is receiving
renewed interest given the numerous side-effects associated with many existing drugs. In …

As the use of medicinal plants continues to gain popularity worldwide, there is dire need for
herbal medicines to be guaranteed in their safety and efficacy. South Africa has a largely …