Human carbonic anhydrase-II (hCA-II) is the most dominant physiologic isoform amongst the
sixteen reported hCA isoforms. Because of its high availability in the different anatomical …

N, N-Dimethylsulfamide (DMS), a newly identified, ubiquitous degradation product of the
fungicide tolylfluanide, has been shown to be a N-nitrosodimethylamine (NDMA) precursor …

In the present work, quantitative structure–activity relationship (QSAR) models of
camptothecin derivatives against DNA Topoisomerase‐I (DNA Topo‐I) were developed by …

In this work, the inhibitory effect of some symmetric sulfamides derived from
phenethylamines were determined against human carbonic anhydrase (hCA) I, and II …

For the prediction of anticancer activity of glycyrrhetinic acid (GA-1) analogs against the
human lung cancer cell line (A-549), a QSAR model was developed by forward stepwise …

In our prior studies, we reported some known antitubercular drugs (rifampicin and
streptomycin) and newly synthesized chalcone derivatives (16–26) tested in vitro against …

Every living molecular machine on planet is constructed across a middle staging of organic
carbon which locked in extremely oxidized structures, such as carbonate minerals (calcite …

Binary Logistic Regression (BLR) has been developed as non-linear models to establish
quantitative structure-activity relationships (QSAR) between structural descriptors and …

The emergence of mutant virus in drug therapy for HIV-1 infection has steadily risen in the
last decade. Inhibition of reverse transcriptase enzyme has emerged as a novel target for the …

Carbonic anhydrases (CAs) are ubiquitous in all kingdoms, such as archaea, bacteria,
algae, andgreenplantsaswellashigheranimalsinclu…. Theyareencoded by five distinct gene …