Antibiotic-induced collateral damage to the microbiota and associated infections
Antibiotics have transformed medicine, saving millions of lives since they were first used to
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …
[HTML][HTML] Reservoirs of antimicrobial resistance in the context of One Health
Highlights•AMR is a leading and constantly growing threat to global health.•The human
microbiome is an important AMR reservoir.•Human–animal–environment interactions favor …
microbiome is an important AMR reservoir.•Human–animal–environment interactions favor …
Mixed strain pathogen populations accelerate the evolution of antibiotic resistance in patients
J Diaz Caballero, RM Wheatley, N Kapel… - Nature …, 2023 - nature.com
Antibiotic resistance poses a global health threat, but the within-host drivers of resistance
remain poorly understood. Pathogen populations are often assumed to be clonal within …
remain poorly understood. Pathogen populations are often assumed to be clonal within …
Recent advances in strategies to combat bacterial drug resistance: antimicrobial materials and drug delivery systems
J Yao, P Zou, Y Cui, L Quan, C Gao, Z Li, W Gong… - Pharmaceutics, 2023 - mdpi.com
Bacterial infection is a common clinical disease. Antibiotics have saved countless lives since
their discovery and are a powerful weapon in the fight against bacteria. However, with the …
their discovery and are a powerful weapon in the fight against bacteria. However, with the …
Within-host evolution of bacterial pathogens in acute and chronic infection
JP Dekker - Annual Review of Pathology: Mechanisms of …, 2024 - annualreviews.org
Bacterial pathogens undergo remarkable adaptive change in response to the selective
forces they encounter during host colonization and infection. Studies performed over the …
forces they encounter during host colonization and infection. Studies performed over the …
[HTML][HTML] Lung microbiome and origins of the respiratory diseases
J Belizário, M Garay-Malpartida, J Faintuch - Current Research in …, 2023 - Elsevier
The studies on the composition of the human microbiomes in healthy individuals, its
variability in the course of inflammation, infection, antibiotic therapy, diets and different …
variability in the course of inflammation, infection, antibiotic therapy, diets and different …
Genomic characterization of Pseudomonas spp. on food: implications for spoilage, antimicrobial resistance and human infection
Background Pseudomonas species are common on food, but their contribution to the
antimicrobial resistance gene (ARG) burden within food or as a source of clinical infection is …
antimicrobial resistance gene (ARG) burden within food or as a source of clinical infection is …
Analysis of metagenome and metabolome disclosed the mechanisms of Dendrobium officinale polysaccharide on DSS-induced ulcerative colitis-affected mice
X Zeng, S Tang, X Dong, M Dong, R Shao, R Liu… - International Journal of …, 2024 - Elsevier
Currently, there is no known cause for ulcerative colitis (UC), an inflammatory bowel disease
that is difficult to treat. This assay aimed to investigate the protective effects and mechanisms …
that is difficult to treat. This assay aimed to investigate the protective effects and mechanisms …
Gut microbiota regulate migration of lymphocytes from gut to lung
S Ni, X Yuan, Q Cao, Y Chen, X Peng, J Lin, Y Li… - Microbial …, 2023 - Elsevier
The community of microorganisms known as gut microbiota that lives in the intestine confers
significant health benefits on its host, primarily in the form of immunological homeostasis …
significant health benefits on its host, primarily in the form of immunological homeostasis …
The microbiome and the gut-lung axis in tuberculosis: interplay in the course of disease and treatment
N Alvarado-Peña, D Galeana-Cadena… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis is a chronic infectious disease caused by Mycobacterium tuberculosis (MTB)
that remains a significant global health challenge. The extensive use of antibiotics in …
that remains a significant global health challenge. The extensive use of antibiotics in …