Advances in translational research of the rare cancer type adrenocortical carcinoma

C Ghosh, J Hu, E Kebebew - Nature Reviews Cancer, 2023 - nature.com
Adrenocortical carcinoma is a rare malignancy with an annual worldwide incidence of 1–2
cases per 1 million and a 5-year survival rate of< 60%. Although adrenocortical carcinoma is …

[HTML][HTML] Feasibility and Activity of Megestrol Acetate in Addition to Etoposide, Doxorubicin, Cisplatin, and Mitotane as First-Line Therapy in Patients with Metastatic …

A Turla, M Laganà, A Abate, V Cremaschi, M Zamparini… - Cancers, 2023 - mdpi.com
Simple Summary Preclinical studies have shown an anti-neoplastic effect of progestins
against adrenal cortical carcinoma. Progestins have a positive effect on patient cenesthesia …

[HTML][HTML] The CDK Inhibitor Dinaciclib Improves Cisplatin Response in Nonseminomatous Testicular Cancer: A Preclinical Study

E Rossini, M Tamburello, A Abate, S Zini, G Ribaudo… - Cells, 2024 - mdpi.com
Background: Most patients with testicular germ cell tumors (GCTs) are treated with cisplatin
(CP)-based chemotherapy. However, some of them may develop CP resistance and …

Letter re: Impact of EDP-M on survival of patients with metastatic adrenocortical carcinoma: A population-based study

M Laganà, D Cosentini, GAM Tiberio… - European Journal of …, 2024 - ejcancer.com
Massimo Tiberio, Sandra Sigala and Alfredo Berruti, Letter re: Impact of EDPM on survival of
patients with metastatic adrenocortical carcinoma: A population-based studyIs EDP-M …

AdrenoCortical Carcinoma: in search of new pharmacological strategies

A Abate - 2024 - iris.unibs.it
Adrenocortical carcinoma (ACC) is a rare malignancy with a dismal prognosis. The
pharmacological approach of ACC is based on mitotane (M) with/without etoposide (E) …