Implication of hippocampal neurogenesis in autism spectrum disorder: Pathogenesis and therapeutic implications

C Liu, J Liu, H Gong, T Liu, X Li… - Current …, 2023 - ingentaconnect.com
Autism spectrum disorder (ASD) is a cluster of heterogeneous neurodevelopmental
conditions with atypical social communication and repetitive sensory-motor behaviors. The …

Neurodevelopmental and functional outcomes following in utero exposure to antiseizure medication: a systematic review

E Honybun, E Cockle, CB Malpas, TJ O'Brien… - Neurology, 2024 - AAN Enterprises
Background and Objectives To undertake a systematic review of the available literature to
examine the relationship between prenatal antiseizure medication (ASM) exposure and …

Risk of Autism after Prenatal Topiramate, Valproate, or Lamotrigine Exposure

S Hernández-Díaz, L Straub, BT Bateman… - … England Journal of …, 2024 - Mass Medical Soc
Background Maternal use of valproate during pregnancy has been associated with an
increased risk of neurodevelopmental disorders in children. Although most studies of other …

Comparative safety of antiseizure medication monotherapy for major malformations

JM Cohen, S Alvestad, CE Cesta, MH Bjørk… - Annals of …, 2023 - Wiley Online Library
Objective This study was undertaken to examine the comparative safety of antiseizure
medication (ASM) monotherapy in pregnancy with respect to risk of major congenital …

Prenatal exposure to antiseizure medication and incidence of childhood-and adolescence-onset psychiatric disorders

JW Dreier, MH Bjørk, S Alvestad, M Gissler… - JAMA …, 2023 - jamanetwork.com
Importance Prenatal antiseizure medication (ASM) exposure has been associated with
adverse early neurodevelopment, but associations with a wider range of psychiatric end …

[HTML][HTML] Adaptive behaviour in children exposed to topiramate in the womb: An observational cohort study

R Knight, J Craig, B Irwin, A Wittkowski… - … : European Journal of …, 2023 - Elsevier
Objective Many women with epilepsy need to continue anti-seizure medications (ASMs)
throughout pregnancy. The current study investigated adaptive behaviour outcomes in …

[HTML][HTML] The impact of adult neurogenesis on affective functions: of mice and men

M Alonso, AC Petit, PM Lledo - Molecular Psychiatry, 2024 - nature.com
In most mammals, new neurons are not only produced during embryogenesis but also after
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …

The pharmacological treatment of epilepsy in adults

T Tomson, J Zelano, YL Dang, P Perucca - Epileptic Disorders, 2023 - Wiley Online Library
The pharmacological treatment of epilepsy entails several critical decisions that need to be
based on an individual careful risk–benefit analysis. These include when to initiate treatment …

Prenatal Exposure to Antiseizure Medications and Risk of Epilepsy in Children of Mothers With Epilepsy

JW Dreier, J Christensen, J Igland, M Gissler… - JAMA network …, 2024 - jamanetwork.com
Importance Use of valproate and certain other antiseizure medications (ASMs) in pregnancy
is associated with abnormal fetal brain development with potential long-term implications for …

[HTML][HTML] European Headache Federation (EHF) critical reappraisal and meta-analysis of oral drugs in migraine prevention–part 3: topiramate

B Raffaelli, D García-Azorín, DM Boucherie… - The Journal of …, 2023 - Springer
Objective Topiramate is a repurposed first-line treatment for migraine prophylaxis. The aim
of this systematic review and meta-analysis is to critically re-appraise the existing evidence …