Emerging arrhythmic risk of autoimmune and inflammatory cardiac channelopathies

PE Lazzerini, PL Capecchi, N El‐Sherif… - Journal of the …, 2018 - Am Heart Assoc
Cardiac arrhythmias are associated with high morbidity and mortality. 1 Specifically,
malignant arrhythmias are a recognized leading cause of sudden cardiac death (SCD) in the …

Proarrhythmic electrophysiological and structural remodeling in rheumatoid arthritis

KHK Patel, TN Jones, S Sattler… - American Journal of …, 2020 - journals.physiology.org
Chronic inflammatory disorders, including rheumatoid arthritis (RA), are associated with a
twofold increase in the incidence of sudden cardiac death (SCD) compared with the healthy …

Electroanatomic and pathologic right ventricular outflow tract abnormalities in patients with Brugada syndrome

M Pieroni, P Notarstefano, A Oliva… - Journal of the American …, 2018 - jacc.org
Background: The prevalence and significance of structural abnormalities in Brugada
syndrome (BrS) are still largely debated. Objectives: The authors investigated the …

Novel insights in the pathomechanism of Brugada syndrome and fever‐related type 1 ECG changes in a preclinical study using human‐induced pluripotent stem cell …

Y Li, H Dinkel, D Pakalniskyte… - Clinical and …, 2023 - Wiley Online Library
Abstract Background Brugada syndrome (BrS) is causing sudden cardiac death (SCD)
mainly at young age. Studying the underlying mechanisms associated with BrS type I …

[HTML][HTML] Longitudinal assessment of structural phenotype in Brugada syndrome using cardiac magnetic resonance imaging

JC Isbister, B Gray, S Offen, L Yeates, C Naoum… - Heart Rhythm O2, 2023 - Elsevier
Background Despite historically being considered a channelopathy, subtle structural
changes have been reported in Brugada syndrome (BrS) on histopathology and cardiac …

Prediction of sudden cardiac death: looking beyond ejection fraction

NA Chatterjee - Current Cardiology Reports, 2023 - Springer
Abstract Purpose of Review Sudden cardiac death (SCD) is a major public health burden
accounting for 15–20% of global mortality. Contemporary guidelines for SCD prevention are …

[HTML][HTML] Lipopolysaccharide modifies sodium current kinetics through ros and pkc signalling in induced pluripotent stem-derived cardiomyocytes from brugada …

Z Liao, Y Li, X Fan, Z Yang, I El-Battrawy… - Journal of …, 2022 - mdpi.com
Studies have suggested a connection between inflammation and arrhythmogenesis of
Brugada syndrome (BrS). However, experimental studies regarding the roles of …

[PDF][PDF] Brugada phenocopies: Current evidence, diagnostic algorithms and a perspective for the future.

G Çinier, G Tse, A Baranchuk - Archives of the Turkish Society …, 2020 - jag.journalagent.com
Brugada syndrome (BrS) is a congenital channelopathy associated with the development of
malignant ventricular arrhythmias and sudden cardiac death. The diagnosis of BrS is made …

[HTML][HTML] A case of cardiac sarcoidosis mimicking Brugada syndrome

VV Rangaswamy, DK Saggu, S Yalagudri… - Indian Pacing and …, 2022 - Elsevier
A 17-year-old boy was admitted for management of ventricular fibrillation (VF) with
intermittent Brugada pattern on ECG. On evaluation, cardiac MRI revealed myocardial scar …

[PDF][PDF] Novel Findings in Brugada Syndrome: A Review in Emergency Department Perspective

AK ERENLER, AY Mehmet Oğuzhan, A BAYDIN - researchgate.net
Brugada Syndrome (BrS) is a life-threatening chanellopathy developing on a genetic basis.
The most common symptoms are syncope and sudden cardiac death. It is characterized by …