Current and possible future therapeutic options for Huntington's disease

MW Ferguson, CJ Kennedy… - Journal of central …, 2022 - journals.sagepub.com
Huntington's disease (HD) is an autosomal neurodegenerative disease that is characterized
by an excessive number of CAG trinucleotide repeats within the huntingtin gene (HTT). HD …

Therapeutic utility of mesenchymal stromal cell (MSC)-based approaches in chronic neurodegeneration: a glimpse into underlying mechanisms, current status, and …

M Rahbaran, AO Zekiy, M Bahramali… - Cellular & Molecular …, 2022 - Springer
Recently, mesenchymal stromal cell (MSC)-based therapy has become an appreciated
therapeutic approach in the context of neurodegenerative disease therapy. Accordingly, a …

Mesenchymal stromal cells (MSCs) for neurodegenerative disease: a promising frontier

A Shariati, R Nemati, Y Sadeghipour… - European journal of cell …, 2020 - Elsevier
Neurodegenerative disorders are a variety of diseases including Alzheimer's (AD),
Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic …

Mesenchymal stem cell-derived extracellular vesicles: An emerging diagnostic and therapeutic biomolecules for neurodegenerative disabilities

M Kandeel, MA Morsy, KM Alkhodair, S Alhojaily - Biomolecules, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) are a type of versatile adult stem cells present in various
organs. These cells give rise to extracellular vesicles (EVs) containing a diverse array of …

Human umbilical cord mesenchymal stem cells: current literature and role in periodontal regeneration

MS Shaikh, Z Shahzad, EA Tash, OS Janjua, MI Khan… - Cells, 2022 - mdpi.com
Periodontal disease can cause irreversible damage to tooth-supporting tissues such as the
root cementum, periodontal ligament, and alveolar bone, eventually leading to tooth loss …

Umbilical cord stem cells: Background, processing and applications

SM Alatyyat, HM Alasmari, OA Aleid… - Tissue and Cell, 2020 - Elsevier
Stem cells have currently gained attention in the field of medicine not only due to their ability
to repair dysfunctional or damaged cells, but also they could be used as drug delivery …

Umbilical cord-derived mesenchymal stem cells in neurodegenerative disorders: from literature to clinical practice

S Reyhani, B Abbaspanah, SH Mousavi - Regenerative medicine, 2020 - Taylor & Francis
Mesenchymal stem cells (MSCs) have provided a promising tool for cell therapy. Umbilical
cord (UC) is one of the best sources of MSCs since its collection is noninvasive, and …

Effect of safranal or candesartan on 3-nitropropionicacid-induced biochemical, behavioral and histological alterations in a rat model of Huntington's disease

NI Shehata, DM Abd EL-Salam, RM Hussein, SM Rizk - Plos one, 2023 - journals.plos.org
3-nitropropionic acid (3-NP) is a potent mitochondrial inhibitor mycotoxin. Systemic
administration of 3-NP can induce Huntington's disease (HD)-like symptoms in experimental …

[HTML][HTML] Applying stem cell therapy in intractable diseases: a narrative review of decades of progress and challenges

APK Ling, YP Wong - Stem Cell Investigation, 2022 - ncbi.nlm.nih.gov
Applying stem cell therapy in intractable diseases: a narrative review of decades of progress
and challenges - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Transplantation of human dental pulp stem cells compensates for striatal atrophy and modulates neuro-inflammation in 3-nitropropionic acid rat model of Huntington's …

N Eskandari, ME Boroujeni, MA Abdollahifar… - Neuroscience …, 2021 - Elsevier
Stem cell-based therapy has recently offered a promising alternative for the remedy of
neurodegenerative disorders like Huntington's disease (HD). Herein, we investigated the …