The pathogenesis and clinical features of diabetic cardiomyopathy have been well-studied
in the past decade, but effective approaches to prevent and treat this disease are limited …

The multifunctional membrane glycoprotein CD36 is expressed in different types of cells and
plays a key regulatory role in cellular lipid metabolism, especially in cardiac muscle. CD36 …

There is a constant high demand for energy to sustain the continuous contractile activity of
the heart, which is met primarily by the β-oxidation of long-chain fatty acids. The control of …

CD36, also known as the scavenger receptor B2, is a multifunctional receptor widely
expressed in various organs. CD36 plays a crucial role in the uptake of long-chain fatty …

Long-chain fatty acids and lipids serve a wide variety of functions in mammalian
homeostasis, particularly in the formation and dynamic properties of biological membranes …

Obesity and insulin resistance are associated with ectopic lipid deposition in multiple
tissues, including the heart. Excess lipid may be stored as triglycerides, but are also shunted …

Transport of long-chain fatty acids across the cell membrane has long been thought to occur
by passive diffusion. However, in recent years there has been a fundamental shift in …

The emerging central role of CD36 in cellular lipid homeostasis and recently obtained
molecular insight in the interplay among metabolic substrates indicate the applicability of …

Fatty acids are a major fuel source used to sustain contractile function in heart and oxidative
skeletal muscle. To meet the energy demands of these muscles, the uptake and β-oxidation …

Objectives: This study was designed to evaluate myocardial substrate and high-energy
phosphate (HEP) metabolism in asymptomatic men with well-controlled, uncomplicated type …