Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
The WHO recognizes human African trypanosomiasis, Chagas disease and the
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
leishmaniases as neglected tropical diseases. These diseases are caused by parasitic …
Biologically active quinoline and quinazoline alkaloids part II
XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …
The role of Platinum (IV)-based antitumor drugs and the anticancer immune response in medicinal inorganic chemistry. A systematic review from 2017 to 2022
S Su, Y Chen, P Zhang, R Ma, W Zhang, J Liu… - European Journal of …, 2022 - Elsevier
Platinum-based antitumor drugs have been used in many types of tumors due to its broad
antitumor spectrum in clinic. Encouraged by the cisplatin's (CDDP) worldwide success in …
antitumor spectrum in clinic. Encouraged by the cisplatin's (CDDP) worldwide success in …
Advancement in leishmaniasis diagnosis and therapeutics: An update
Leishmaniasis is regarded as a neglected tropical disease by World Health Organization
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
(WHO) and is ranked next to malaria as the deadliest protozoan disease. The primary …
Searching for drugs for Chagas disease, leishmaniasis and schistosomiasis: a review
Chagas disease, leishmaniasis and schistosomiasis are neglected diseases (NDs) and are
a considerable global challenge. Despite the huge number of people infected, NDs do not …
a considerable global challenge. Despite the huge number of people infected, NDs do not …
Antileishmanial drug discovery and development: time to reset the model?
AI Olias-Molero, C de la Fuente, M Cuquerella… - Microorganisms, 2021 - mdpi.com
Leishmaniasis is a vector-borne parasitic disease caused by Leishmania species. The
disease affects humans and animals, particularly dogs, provoking cutaneous …
disease affects humans and animals, particularly dogs, provoking cutaneous …
Antileishmanial drug discovery: Comprehensive review of the last 10 years
Leishmaniasis, a group of diseases caused by hemoflagellate obligate intracellular protozoa
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …
[HTML][HTML] Quinoline derivatives as possible lead compounds for anti-malarial drugs: Spectroscopic, DFT and MD study
In this work we report spectroscopic characterization and reactivity study by density
functional theory (DFT) and molecular dynamics (MD) simulations of two quinoline …
functional theory (DFT) and molecular dynamics (MD) simulations of two quinoline …
The role of natural anti-parasitic guided development of synthetic drugs for leishmaniasis
Leishmaniasis is a parasitic disease and categorised as a neglected tropical disease (NTD).
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …
Each year, between 70, 0000 and 1 million new cases are believed to occur. There are …
Ligational behavior of bidentate nitrogen–oxygen donor 8‐quinolinolazodye toward Ni2+ and Zn2+ ions: Preparation, spectral, thermal, experimental, theoretical …
MG Abd El‐Nasser… - Applied Organometallic …, 2023 - Wiley Online Library
The 5‐(4‐aryl azo)‐8‐hydroxyquinolines (L1–L3) and their metal complexes with Ni2+ and
Zn2+ have been produced. Various spectroscopic techniques have been employed to …
Zn2+ have been produced. Various spectroscopic techniques have been employed to …