Irradiation of pharmaceuticals: A literature review

GP Jacobs - Radiation Physics and Chemistry, 2022 - Elsevier
Regulatory authorities require pharmaceuticals to be sterilized wherever practicable by a
terminal sterilization method that is sterilized in the final container rather than by aseptic …

The effects of gamma irradiation on diclofenac sodium, liposome and niosome ingredients for rheumatoid arthritis

A Özer, S Turker, S Colak, M Korkmaz… - … Medicine and Applied …, 2013 - akjournals.com
The use of gamma rays for the sterilization of pharmaceutical raw materials and dosage
forms is an alternative method for sterilization. However, one of the major problems of the …

Gamma-irradiated liposome/niosome and lipogelosome/niogelosome formulations for the treatment of rheumatoid arthritis

S Turker, A Yekta Özer, E Kiliç, M Özalp… - … Medicine and Applied …, 2013 - akjournals.com
Abstract Treatment of rheumatoid arthritis by intraarticular administration of anti-inflammatory
drugs encapsulated in drug delivery systems, such as liposomes/niosomes and …

Radiation sterilization of antibiotics in solid state

K Kilińska, P Zalewski - Current Analytical Chemistry, 2021 - ingentaconnect.com
Background: Radiation sterilization is a promising method of obtaining sterile active
pharmaceutical ingredients (API), excipients and formulations. One of the best methods of …

Ionizing radiation used in drug sterilization, characterization of radical intermediates by electron spin resonance (ESR) analyses

Ş Çolak - Evolution of Ionizing Radiation Research; IntechOpen …, 2015 - books.google.com
In this study, the feasibility of radiation sterilization of drugs/drug raw materials is
investigated by using Electron Spin Resonance (ESR) spectroscopy. Experimental data and …

Validation of the radiation sterilization of pharmaceuticals

GP Jacobs - Handbook of Validation in Pharmaceutical Processes …, 2021 - taylorfrancis.com
Gamma irradiation for the sterilization of pharmaceuticals has been a recognized method of
sterilization for over 50 years. However, radiation sterilization may also be carried out using …

Electron Spin Resonance Spectroscopy Investigations on Radiosterilization Feasibilities of Sulfadiazine, Sulfamethoxydiazine and Sulfaquinoxaline

Ş Çolak - Electron Spin Resonance Spectroscopy in Medicine, 2019 - Springer
In this study, the spectroscopic features of the radiolytic intermediates created upon gamma
irradiation of sulfadiazine (SDZ), sulfamethoxydiazine (SMDZ) and sulfaquinoxaline (SQX) …

Electron-irradiation-induced decomposition of sulfonamides

Z Liu, H Zhang, B Shao, R Zhao - … Methods in Physics Research Section B …, 2006 - Elsevier
The effect of electron irradiation on sulfanilamide (SA) and sulfadimethoxine (SDM)
solutions has been studied at various irradiation doses and various original concentrations …

Sterilization: Radiation

GP Jacobs - Encyclopedia of Pharmaceutical Technology, 2013 - api.taylorfrancis.com
Since the early 1960's gamma (and later electron-beam) irradiation has been a recognized
method for sterilization of pharmaceutical products. Gamma irradiation first appeared in the …

[引用][C] 辐照降解技术应用及影响因素分析

谢芳, 哈益明, 王锋 - 核农学报, 2008