The endoplasmic reticulum (ER) is one of the most important cellular organelles and is
essential for cell homeostasis. Upon external stimulation, ER stress induces the unfolded …

The endoplasmic reticulum (ER) is a ubiquitous organelle that is vital to the life of eukaryotic
cells. It synthesizes essential lipids and proteins and initiates the glycosylation of …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

In the tumor microenvironment, cancer cells experience hypoxia resulting in the
accumulation of misfolded/unfolded proteins largely in the endoplasmic reticulum (ER) …

Both O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) and endoplasmic reticulum-
phagy (ER-phagy) are well-characterized conserved adaptive regulatory mechanisms that …

Abstract The reticulon-3 (RTN3)-driven targeting complex promotes clearance of misfolded
prohormones from the endoplasmic reticulum (ER) for lysosomal destruction by ER-phagy …

The nephrotoxic secondary fungal metabolite ochratoxin A (OTA) is ubiquitously existed in
foodstuffs and feeds. Although our earlier research provided preliminary evidence that …

The endoplasmic reticulum (ER) is a dynamic organelle and a reliable performer for
precisely folded proteins. To maintain its function and integrity, arrays of sensory and quality …

Autophagy is considered as an important mechanism for maintaining homeostasis and
responsible for the degradation of superfluous or potentially toxic components and …

The incidence of low back pain caused by lumbar disc degeneration is high, and it can lead
to loss of work ability and impose heavy social and economic burdens. The pathogenesis of …