Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder

N Eissa, M Al-Houqani, A Sadeq, SK Ojha… - Frontiers in …, 2018 - frontiersin.org
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …

Update on PET imaging biomarkers in the diagnosis of neuropsychiatric disorders

S Hellwig, K Domschke - Current opinion in neurology, 2019 - journals.lww.com
The role of PET imaging in the biomarker-guided diagnostic process of neuropsychiatric
disorders has been increasingly acknowledged in recent years. Future prospective studies …

Functional connectivity of the raphe nucleus as a predictor of the response to selective serotonin reuptake inhibitors in obsessive-compulsive disorder

M Kim, S Kwak, YB Yoon, YB Kwak, T Kim… - …, 2019 - nature.com
Selective serotonin reuptake inhibitors (SSRIs) are first-line pharmacological agents for
treating obsessive-compulsive disorder (OCD). However, because nearly half of patients …

Double blind controlled study of adding folic acid to fluoxetine in the treatment of OCD

Ü Tural, A Çorapçıoğlu, Ş Boşgelmez, G Köroğlu… - Psychiatria …, 2019 - hrcak.srce.hr
Background: Folate is important for the synthesis of serotonin the neurotransmitter which
plays a main role in OCD. We, therefore, explored the efficacy of folic acid as add on …

Effect of escitalopram on serum GDNF and BDNF levels and 5-HT level of brain tissue of obsessive–compulsive disorder rats

HR Guo, BL Huang, YL Wang, YY Zhang… - Cellular and Molecular …, 2020 - Springer
The present study aims to discuss the effect of escitalopram in glial cell line-derived
neurotrophic factor (GDNF), brain-derived neurotrophic factor (BDNF) levels, and 5 …

[HTML][HTML] Early-onset obsessive-compulsive disorder: Sociodemographic and clinical characterization of a large outpatient cohort

N Girone, B Benatti, C Bucca, N Cassina… - Journal of Psychiatric …, 2024 - Elsevier
Introduction Obsessive-compulsive disorder (OCD) is a prevalent and disabling condition
characterized by a wide variety of phenotypic expressions. Several studies have reinforced …

Serotonergic underpinnings of obsessive‐compulsive disorder: A systematic review and meta‐analysis of neuroimaging findings

M Pastre, BV Occéan, V Boudousq… - Psychiatry and …, 2024 - Wiley Online Library
Obsessive‐compulsive disorder (OCD) is a frequent and disabling condition, with many
patients being treatment‐resistant. Improved understanding of its neurobiology is vital for …

[图书][B] Clinical neuroscience: foundations of psychological and neurodegenerative disorders

L Weyandt - 2018 - taylorfrancis.com
Clinical Neuroscience offers a comprehensive overview of the biological bases of major
psychological and psychiatric disorders, and provides foundational information regarding …

Exploring Association Between Serotonin and Neurogenesis Related Genes in Obsessive-Compulsive Disorder in Chinese Han People: Promising Association …

M Deng, Y Wang, S Yu, Q Fan, J Qiu, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Obsessive-compulsive disorder (OCD) is a deliberating disorder with complex genetic and
environmental etiologies. Hypotheses about OCD mainly include dysregulated …

Pathophysiology of obsessive-compulsive and related disorders

D Dougherty, S Rauch… - The American Psychiatric …, 2020 - books.google.com
In this chapter, we review neurochemical models, neuroendocrine factors, and
immunological etiology as putative mechanisms leading to striatal pathology in OCD. We …