2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Developed by the task force for the …

K Zeppenfeld, J Tfelt-Hansen, M De Riva… - European heart …, 2022 - academic.oup.com
4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

Pre-participation cardiovascular evaluation for athletic participants to prevent sudden death: Position paper from the EHRA and the EACPR, branches of the ESC …

L Mont, A Pelliccia, S Sharma, A Biffi, M Borjesson… - Ep …, 2017 - academic.oup.com
Sudden cardiac death (SCD) associated with athletic activity is a rare but devastating event.
Victims are usually young and apparently healthy, and while many of these deaths remain …

Human-iPSC-derived cardiac stromal cells enhance maturation in 3D cardiac microtissues and reveal non-cardiomyocyte contributions to heart disease

E Giacomelli, V Meraviglia, G Campostrini, A Cochrane… - Cell stem cell, 2020 - cell.com
Cardiomyocytes (CMs) from human induced pluripotent stem cells (hiPSCs) are functionally
immature, but this is improved by incorporation into engineered tissues or forced contraction …

Molecular mechanisms of arrhythmogenic cardiomyopathy

KM Austin, MA Trembley, SF Chandler… - Nature Reviews …, 2019 - nature.com
Arrhythmogenic cardiomyopathy is a genetic disorder characterized by the risk of life-
threatening arrhythmias, myocardial dysfunction and fibrofatty replacement of myocardial …

Pericardial Delivery of SDF‐1α Puerarin Hydrogel Promotes Heart Repair and Electrical Coupling

L Luo, Y Li, Z Bao, D Zhu, G Chen, W Li… - Advanced …, 2024 - Wiley Online Library
The stromal‐derived factor 1α/chemokine receptor 4 (SDF‐1α/CXCR4) axis contributes to
myocardial protection after myocardial infarction (MI) by recruiting endogenous stem cells …

Sudden cardiac death prediction in arrhythmogenic right ventricular cardiomyopathy: a multinational collaboration

J Cadrin-Tourigny, LP Bosman, W Wang… - Circulation …, 2021 - Am Heart Assoc
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with
ventricular arrhythmias (VA) and sudden cardiac death (SCD). A model was recently …

Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications

MZ Totland, NL Rasmussen, LM Knudsen… - Cellular and Molecular …, 2020 - Springer
Gap junctions consist of arrays of intercellular channels that enable adjacent cells to
communicate both electrically and metabolically. Gap junctions have a wide diversity of …

Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype

M Cerrone, X Lin, M Zhang, E Agullo-Pascual… - Circulation, 2014 - Am Heart Assoc
Background—Brugada syndrome (BrS) primarily associates with the loss of sodium channel
function. Previous studies showed features consistent with sodium current (I Na) deficit in …

Subepicardial cardiomyopathy: a disease underlying J-wave syndromes and idiopathic ventricular fibrillation

C Miles, BJ Boukens, C Scrocco, AAM Wilde… - Circulation, 2023 - Am Heart Assoc
Brugada syndrome (BrS), early repolarization syndrome (ERS), and idiopathic ventricular
fibrillation (iVF) have long been considered primary electrical disorders associated with …

Diagnostic and therapeutic strategies for arrhythmogenic right ventricular dysplasia/cardiomyopathy patient

W Wang, CA James, H Calkins - Ep Europace, 2019 - academic.oup.com
Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is a rare inherited
heart muscle disease characterized by ventricular tachyarrhythmia, predominant right …