Molecular dynamics simulations of PAMAM and PPI dendrimers using the GROMOS-Compatible 2016H66 Force Field

MC Ramos, VAC Horta, BAC Horta - Journal of chemical …, 2019 - ACS Publications
A systematic evaluation of the accuracy of the GROMOS-compatible 2016H66 force field in
the simulation of dendrimers is performed. More specifically, the poly (amido …

Molecular dynamics simulation studies of hyperbranched polyglycerols and their encapsulation behaviors of small drug molecules

C Yu, L Ma, K Li, S Li, Y Liu, Y Zhou… - Physical Chemistry …, 2016 - pubs.rsc.org
Hyperbranched polyglycerol (HPG) is one of the most important hyperbranched polymers
(HBPs) due to its interesting properties and applications. Herein, the conformation of HPGs …

Elucidation of the cellular uptake mechanisms of polycationic HYDRAmers

J Russier, M Grillaud, A Bianco - Bioconjugate Chemistry, 2015 - ACS Publications
Dendrimers and dendrons appeared to potentially fulfill the requirements for being good and
well-defined carriers in drug and gene delivery applications. We recently demonstrated that …

Coarse‐Grained and Atomistic Simulations for the G = 4 PAMAM‐EDA Dendrimer

JJ Freire, AM Rubio, C McBride - Macromolecular Theory and …, 2015 - Wiley Online Library
Extensive fully‐atomistic molecular dynamics simulations have been performed for the G= 4
generation of the dendrimer PAMAM‐EDA in water, with fully protonated and non …

Evaluation of electrostatic binding of PAMAM dendrimers and charged phthalocyanines by fluorescence correlation spectroscopy

E Garcia-Fernandez, PMR Paulo… - Physical Chemistry …, 2015 - pubs.rsc.org
We have assessed host–guest interactions between PAMAM dendrimers and charged
phthalocyanine probes by Fluorescence Correlation Spectroscopy (FCS). Our results show …

Impact of dendrimer terminal group chemistry on blockage of the anthrax toxin channel: a single molecule study

G Yamini, N Kalu, EM Nestorovich - Toxins, 2016 - mdpi.com
Nearly all the cationic molecules tested so far have been shown to reversibly block K+
current through the cation-selective PA63 channels of anthrax toxin in a wide nM–mM range …

Calculation of conformational properties and rouse relaxation times of PAMAM‐EDA dendrimers under different pH conditions

JJ Freire, AM Rubio, C McBride - Macromolecular Theory and …, 2016 - Wiley Online Library
A Monte Carlo study has been performed for protonated and non‐protonated coarse‐
grained PAMAM‐EDA of generations (G) ranging from 2 to 6. This study calculates sizes …

Effects of PAMAM dendrimers on model and biological membranes

M Wilde - 2021 - centaur.reading.ac.uk
Poly (amidoamine)(PAMAM) dendrimers are nanosized, highly defined, hyperbranched
polymeric vehicles designed for targeted delivery of drugs or bioactive molecules. Whilst …

Local hydrodynamics of solvent near diffusing dendrimers: A test of the new Stokes–Einstein relation

X Zhang, AA Gray‐Weale - Journal of Polymer Science Part B …, 2017 - Wiley Online Library
We have reported a new Stokes–Einstein relation (SER) for size determination and tested it
by different nanoparticles. We assumed that the breakdown for SER results from local …

[图书][B] Nanoparticle behavior in biological gels and biofluids: The impact of interactions with charged biogels and the formation of protein coronas on nanoparticles

X Zhang - 2015 - search.proquest.com
With the rapid growth of nanotechnology, situations where nanomaterials will interact with
biological systems will unquestionably grow. Therefore, it is increasingly understood that …