[HTML][HTML] The role of SOX family members in solid tumours and metastasis

D Grimm, J Bauer, P Wise, M Krüger… - Seminars in cancer …, 2020 - Elsevier
Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …

Tenascin-C at a glance

KS Midwood, M Chiquet, RP Tucker… - Journal of cell …, 2016 - journals.biologists.com
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several
molecular forms that are created through alternative splicing and protein modifications. It is …

METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer

X Chen, MU Xu, X Xu, K Zeng, X Liu, B Pan, C Li… - Molecular cancer, 2020 - Springer
Background Colorectal cancer (CRC) is one of the leading causes of tumor-related death
worldwide, and its main cause of death is distant metastasis. Methyltransferase-like 14 …

Annotation of functional variation in personal genomes using RegulomeDB

AP Boyle, EL Hong, M Hariharan, Y Cheng… - Genome …, 2012 - genome.cshlp.org
As the sequencing of healthy and disease genomes becomes more commonplace, detailed
annotation provides interpretation for individual variation responsible for normal and …

[HTML][HTML] Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming

N Tiwari, VK Tiwari, L Waldmeier, PJ Balwierz… - Cancer cell, 2013 - cell.com
Gene expression profiling has uncovered the transcription factor Sox4 with upregulated
activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in normal and …

SOX4: The unappreciated oncogene

CS Moreno - Seminars in cancer biology, 2020 - Elsevier
SOX4 is an essential developmental transcription factor that regulates stemness,
differentiation, progenitor development, and multiple developmental pathways including …

UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions

MA Hume, LA Barrera, SS Gisselbrecht… - Nucleic acids …, 2015 - academic.oup.com
Abstract The Universal PBM Resource for Oligonucleotide Binding Evaluation (UniPROBE)
serves as a convenient source of information on published data generated using universal …

Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation

L Poliseno, L Salmena, L Riccardi, A Fornari… - Science …, 2010 - science.org
PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a tumor suppressor
that antagonizes signaling through the phosphatidylinositol 3-kinase–Akt pathway. We have …

Advances in tenascin-C biology

KS Midwood, T Hussenet, B Langlois… - Cellular and molecular life …, 2011 - Springer
Tenascin-C is an extracellular matrix glycoprotein that is specifically and transiently
expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …

MicroRNA‐138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF‐1α

YM Yeh, CM Chuang, KC Chao… - International journal of …, 2013 - Wiley Online Library
Metastasis is the major factor affecting patient survival in ovarian cancer. However, its
molecular mechanisms remain unclear. Our study used isogenic pairs of low‐and high …