[HTML][HTML] The role of SOX family members in solid tumours and metastasis
Cancer is a heavy burden for humans across the world with high morbidity and mortality.
Transcription factors including sex determining region Y (SRY)-related high-mobility group …
Transcription factors including sex determining region Y (SRY)-related high-mobility group …
Tenascin-C at a glance
KS Midwood, M Chiquet, RP Tucker… - Journal of cell …, 2016 - journals.biologists.com
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several
molecular forms that are created through alternative splicing and protein modifications. It is …
molecular forms that are created through alternative splicing and protein modifications. It is …
METTL14-mediated N6-methyladenosine modification of SOX4 mRNA inhibits tumor metastasis in colorectal cancer
X Chen, MU Xu, X Xu, K Zeng, X Liu, B Pan, C Li… - Molecular cancer, 2020 - Springer
Background Colorectal cancer (CRC) is one of the leading causes of tumor-related death
worldwide, and its main cause of death is distant metastasis. Methyltransferase-like 14 …
worldwide, and its main cause of death is distant metastasis. Methyltransferase-like 14 …
Annotation of functional variation in personal genomes using RegulomeDB
As the sequencing of healthy and disease genomes becomes more commonplace, detailed
annotation provides interpretation for individual variation responsible for normal and …
annotation provides interpretation for individual variation responsible for normal and …
[HTML][HTML] Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming
Gene expression profiling has uncovered the transcription factor Sox4 with upregulated
activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in normal and …
activity during TGF-β-induced epithelial-mesenchymal transition (EMT) in normal and …
SOX4: The unappreciated oncogene
CS Moreno - Seminars in cancer biology, 2020 - Elsevier
SOX4 is an essential developmental transcription factor that regulates stemness,
differentiation, progenitor development, and multiple developmental pathways including …
differentiation, progenitor development, and multiple developmental pathways including …
UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions
MA Hume, LA Barrera, SS Gisselbrecht… - Nucleic acids …, 2015 - academic.oup.com
Abstract The Universal PBM Resource for Oligonucleotide Binding Evaluation (UniPROBE)
serves as a convenient source of information on published data generated using universal …
serves as a convenient source of information on published data generated using universal …
Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation
L Poliseno, L Salmena, L Riccardi, A Fornari… - Science …, 2010 - science.org
PTEN (phosphatase and tensin homolog deleted on chromosome 10) is a tumor suppressor
that antagonizes signaling through the phosphatidylinositol 3-kinase–Akt pathway. We have …
that antagonizes signaling through the phosphatidylinositol 3-kinase–Akt pathway. We have …
Advances in tenascin-C biology
KS Midwood, T Hussenet, B Langlois… - Cellular and molecular life …, 2011 - Springer
Tenascin-C is an extracellular matrix glycoprotein that is specifically and transiently
expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …
expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …
MicroRNA‐138 suppresses ovarian cancer cell invasion and metastasis by targeting SOX4 and HIF‐1α
YM Yeh, CM Chuang, KC Chao… - International journal of …, 2013 - Wiley Online Library
Metastasis is the major factor affecting patient survival in ovarian cancer. However, its
molecular mechanisms remain unclear. Our study used isogenic pairs of low‐and high …
molecular mechanisms remain unclear. Our study used isogenic pairs of low‐and high …